A0A1Q4I077 · A0A1Q4I077_9MYCO

Function

function

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Energy metabolism; oxidative phosphorylation.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncytochrome-c oxidase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processelectron transport coupled proton transport
Biological Processoxidative phosphorylation
Biological Processrespiratory electron transport chain

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome c oxidase subunit 1
  • EC number

Gene names

    • ORF names
      BRW65_04890

Organism names

  • Taxonomic identifier
  • Strain
    • M11
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium

Accessions

  • Primary accession
    A0A1Q4I077

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane40-62Helical
Transmembrane82-109Helical
Transmembrane121-142Helical
Transmembrane170-196Helical
Transmembrane208-234Helical
Transmembrane254-278Helical
Transmembrane290-311Helical
Transmembrane317-339Helical
Transmembrane360-380Helical
Transmembrane400-418Helical
Transmembrane430-452Helical
Transmembrane472-493Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain23-537Cytochrome oxidase subunit I profile
Region565-586Disordered

Sequence similarities

Belongs to the heme-copper respiratory oxidase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    586
  • Mass (Da)
    65,060
  • Last updated
    2017-04-12 v1
  • Checksum
    EDAC04A2468FFDE1
MTAEAPPLGELEAVRPYPDRTGPKGNLVYKLITTTDHKMIGIMYTVTCFVFFFIGGLMALLMRTELAAPGLQFLSNEQYNQLFTMHGTIMLLLYATPVVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGGLTAAAGFIVPGGAADFGWTAYTPLSDAVHSPGAGGDLWITGLIVAGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNIMVTSILILIAFPILTAALFGLAADRHLGAHVYDAANGGVLLWQHLFWFFGHPEVYIIALPFFGIVTEIIPVFSRKPVFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWKGQITFETPMLFSVGFLVTFLLGGLTGVMLASPPLDFHVTDTYFVVAHFHYVLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGDMGMPRRYADYLASDGFQGLNIVSTIGAFILGASMFPFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERLRAEAHVGRHATALESPKGFGPRTEADRSTPDQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MPNT01000003
EMBL· GenBank· DDBJ
OJZ75353.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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