A0A1Q4HMI4 · A0A1Q4HMI4_9MYCO
- ProteinCytochrome bc1 complex cytochrome c subunit
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids270 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H+(out)
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 61 | heme c 1 (UniProtKB | ChEBI); covalent | ||||
Sequence: C | ||||||
Binding site | 64 | heme c 1 (UniProtKB | ChEBI); covalent | ||||
Sequence: C | ||||||
Binding site | 65 | Fe (UniProtKB | ChEBI) of heme c 1 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 162 | heme c 2 (UniProtKB | ChEBI); covalent | ||||
Sequence: C | ||||||
Binding site | 165 | heme c 2 (UniProtKB | ChEBI); covalent | ||||
Sequence: C | ||||||
Binding site | 166 | Fe (UniProtKB | ChEBI) of heme c 2 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | respirasome | |
Molecular Function | heme binding | |
Molecular Function | iron ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytochrome bc1 complex cytochrome c subunit
- EC number
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycolicibacterium
Accessions
- Primary accessionA0A1Q4HMI4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 249-268 | Helical | ||||
Sequence: MAIWIIGMVAAVAMTLWIGA |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-30 | |||||
Sequence: MTSKSRRRLRRRLSAAVLLLLGLSAAGVTA | ||||||
Chain | PRO_5038219483 | 31-270 | Cytochrome bc1 complex cytochrome c subunit | |||
Sequence: ATLTPTPQVAVADESQSALLRTGEQLFETSCISCHGANLQGVPDRGPSLIGTGEAAVYFQVSTGRMPAMRGEAQAPRKAPVFDEHQTDALGAYVQANGGGPVVPREANGHIADASLLSGDVARGGDLFRLNCASCHNFTGKGGALSSGKYAPDLGEAAKVPAQVYTAMLTGPQNMPKFSDRQLSPEEKADIVTYVSEAANTPDPGGYGLGGFGPTTEGMAIWIIGMVAAVAMTLWIGARA |
Post-translational modification
Binds 2 heme c groups covalently per subunit.
Interaction
Subunit
The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 48-128 | Cytochrome c | ||||
Sequence: ALLRTGEQLFETSCISCHGANLQGVPDRGPSLIGTGEAAVYFQVSTGRMPAMRGEAQAPRKAPVFDEHQTDALGAYVQANG | ||||||
Domain | 149-229 | Cytochrome c | ||||
Sequence: GDVARGGDLFRLNCASCHNFTGKGGALSSGKYAPDLGEAAKVPAQVYTAMLTGPQNMPKFSDRQLSPEEKADIVTYVSEAA |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length270
- Mass (Da)27,929
- Last updated2017-04-12 v1
- ChecksumBF1F36648383AC01