A0A1Q4D8B3 · A0A1Q4D8B3_9HYPH

Function

function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphomonoester.
    EC:3.1.26.3 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

123620406080100120140160180200220
TypeIDPosition(s)Description
Binding site48Mg2+ (UniProtKB | ChEBI)
Active site52
Binding site121Mg2+ (UniProtKB | ChEBI)
Active site124
Binding site124Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmetal ion binding
Molecular Functionribonuclease III activity
Molecular FunctionrRNA binding
Biological ProcessmRNA processing
Biological ProcessrRNA processing
Biological ProcesssiRNA processing
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease 3
  • EC number
  • Alternative names
    • Ribonuclease III
      (RNase III
      )

Gene names

    • Name
      rnc
    • ORF names
      BGP08_12205

Organism names

Accessions

  • Primary accession
    A0A1Q4D8B3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain8-135RNase III
Domain160-229DRBM
Region203-236Disordered

Sequence similarities

Belongs to the ribonuclease III family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    236
  • Mass (Da)
    25,620
  • Last updated
    2017-04-12 v1
  • Checksum
    8BA0ACD5F8870D00
MSRKAKIRTDVESTIGYQFTDKTLLERALTHISAASGGNRIASYQRLEFLGDHVLGLVVSDMLFRAFPKANEGELSRRLADLVRKDTCADIARAMDLGPAMLLGNSESQAGGRRRTTILADMCEALVGAVFVDGGYSAAAAVIEKFWHERLVKPAKPLRDAKTMLQEWAQARGLPTPTYRETGRSGPHHNPVFKVAVVLPGKPDAEGSGKSKRAAEQAAAATMLEREGVNPDKFEA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MKWA01000026
EMBL· GenBank· DDBJ
OJY40601.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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