A0A1Q4D892 · A0A1Q4D892_9HYPH

Function

function

Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site123-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site14-151-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site233-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Active site48Proton acceptor
Binding site501-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site551-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Active site75Proton acceptor
Binding site1051-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Site156Transition state stabilizer
Active site199Proton donor
Binding site2003-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site221-2223-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionpyridoxine 5'-phosphate synthase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine 5'-phosphate synthase
  • EC number
  • Short names
    PNP synthase

Gene names

    • Name
      pdxJ
    • ORF names
      BGP08_12220

Organism names

Accessions

  • Primary accession
    A0A1Q4D892

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer; tetramer of dimers.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the PNP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    254
  • Mass (Da)
    26,735
  • Last updated
    2017-04-12 v1
  • Checksum
    3B8D8FB8D4C64703
MTGHAVPRLGVNVDHVATIRNARGGRLPDPVRAANLAIAAGADGITAHLREDRRHIRDDDMARLKAEIDKPLNFEMAATREMVAIALRTAPHASCIVPERREERTTEGGLDAAGQRAQLAPMIDELRGAGIRVSLFIAADPAQIEAAASLRAPVIELHTGAWCDAIADGHADRAAAEWSRIVAGTALGAKLGLEVHAGHGLAFDTAERIAALPAIAELNIGHFLIGEAVFDGLPSAIGLMKDAIARGRKAARLA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MKWA01000026
EMBL· GenBank· DDBJ
OJY40604.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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