A0A1P8WBU5 · A0A1P8WBU5_9PLAN

Function

function

This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

  • Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.
    EC:3.4.23.36 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; lipoprotein biosynthesis (signal peptide cleavage).

Features

Showing features for active site.

119120406080100120140160180
TypeIDPosition(s)Description
Active site137
Active site161

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionaspartic-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lipoprotein signal peptidase
  • EC number
  • Alternative names
    • Prolipoprotein signal peptidase
    • Signal peptidase II
      (SPase II
      )

Gene names

    • Name
      lspA
    • ORF names
      Fuma_01092

Organism names

  • Taxonomic identifier
  • Strain
    • NH11
  • Taxonomic lineage
    Bacteria > Planctomycetota > Planctomycetia > Planctomycetales > Planctomycetaceae > Fuerstiella

Accessions

  • Primary accession
    A0A1P8WBU5

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane69-89Helical
Transmembrane96-115Helical

Keywords

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the peptidase A8 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    191
  • Mass (Da)
    20,951
  • Last updated
    2017-04-12 v1
  • Checksum
    1C70D9CA104CB151
MNRLPRNRAVVFGIITASMLAVDLWSKTAAFTAFPLRNGGPWLIDSTAVRFRFFTSLNEGALWGFGQGFAWAFALLSVAAFVGVLYWLFVMKAAESLWLTISLAFVSAGTLGNLYDRLGLHGIRLPGQDQPIQAVRDFFHFQFGGTVQNPGLDWAIFNVADICLVCGAGMLMIQSLFAPPEPTTQPVRTES

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP017641
EMBL· GenBank· DDBJ
APZ91504.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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