A0A1P8STS5 · A0A1P8STS5_9POTY

Function

Catalytic activity

  • Hydrolyzes glutaminyl bonds, and activity is further restricted by preferences for the amino acids in P6 - P1' that vary with the species of potyvirus, e.g. Glu-Xaa-Xaa-Tyr-Xaa-Gln-|-(Ser or Gly) for the enzyme from tobacco etch virus. The natural substrate is the viral polyprotein, but other proteins and oligopeptides containing the appropriate consensus sequence are also cleaved.
    EC:3.4.22.44 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenthelical viral capsid
Cellular Componenthost cell cytoplasmic vesicle
Cellular Componentmembrane
Cellular Componentvesicle
Molecular FunctionATP binding
Molecular Functioncysteine-type peptidase activity
Molecular Functionhelicase activity
Molecular Functionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Molecular FunctionRNA binding
Molecular FunctionRNA-dependent RNA polymerase activity
Molecular Functionstructural molecule activity
Biological ProcessDNA-templated transcription
Biological Processproteolysis
Biological Processviral RNA genome replication

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Polyprotein

Organism names

  • Taxonomic identifier
  • Strain
    • LYJN
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Pisuviricota > Stelpaviricetes > Patatavirales > Potyviridae > Bymovirus

Accessions

  • Primary accession
    A0A1P8STS5

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane264-283Helical
Transmembrane295-317Helical
Transmembrane338-357Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-24Disordered
Domain473-615Helicase ATP-binding
Domain1360-1575Peptidase C4
Domain1854-1978RdRp catalytic

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    2,404
  • Mass (Da)
    268,941
  • Last updated
    2017-04-12 v1
  • Checksum
    EBB068C4E6F5EE10
MEQTAAQTAARHATHTNSAQEQPPVSPMNLFANFVAPELFYASNVEKIKSIMRMRSTTRIIDAISRDFELVAFLILSPAHLMQLETTLRCEMKSSIVPIANSDAGFETCAVLKTALDGMKYHFGTTTLEQGWTSMMRHADSCLQESSSSAVAMLQTQVQKVGSLLISGKNRVESCELYVLHLTARAFRTEYGLKGTCFGEHCALLHDLKACVCGTVPKEFLWAKTKKHSIFTIPEWIARTPTDCFMLCLRAIPIFRRCTMAMSLLYWSCVATVNFPSVMAFLFKRQFTKYIAHSFAKHSIYFLMLGIVALLWAFRTYASKNPKIALQARSANEKEKKLMMLLASAVGITYLFDYDIAEALGNSLHKISRLSSYLMDDHQGIASRMFSASYGLQAGNNTEDAVTTIISDLLSVTFQIVDEDATAGALEEVSDTTFSSWVSVNTLAGRNMSRPLQYPVNQTYPLTPMNVLLQAQAMVDSDNCWSMVVGHTGSGKSTYLPVQYSNYLAKKPERRQQILVCEPTQAATENVCSGIAANLGRAVYGRHEGWSRMGDHCIQVMTYGSALQCHAMDPGFISTFDAIFLDEAHDVKEHSLVFESICNNFKSVRKFYVSATPRDGSSCPDATRKFPLTVQQSVCDSYKKFIAAQGGHDLLDVTRHDTVLVFLAGRPECVKAANAWNASITGEKRAFSLSSDNFTTDFAMLTERLKTHKTIIFTTNIIETGVTLSVDCVVDFGYTMRPSLDLNHKTLRLERRRVTANERKQRIGRAGRLKEGYAIVCGDEDRSVNVVSPDVLYGAALLSFKHNVPFYMNDTFESSWLEGVTKSQADTMTIFKLPIFLTRDLVNSDGSVAKEFLDILKKHQFTTSDIKQAPHSIARHLFPTWASYFALFQSINYGEEKDEIPSNLRHARVPFSISTLSKFDWNALALACEQHRPTVTSSFQGLDQPARVVTLQTNSANILGSIAHLCNMRNNYKALIDSNNHVKQSMATNVMFKWFSSSRITADLDRNLSRCLANLSVVETTISSLKQISAGNSQVMASPTLQSHLENIIELQSNDMLTDETLSNALGIFNPKTNLFLLLATKGFKLVYVICLLILINLIYRLLSHWRAWLKNKNDNVDLDALTNTMTVQEGSEILKEVSKMTPAMRREVTKDMKVAVANNDSTFSFVFPHEHIDLEGKGNKYRPREDARLMYSTRDDATFDTWNEKAKEKRKKISDRAEPEMRQPYQKRPYYNFYDLQTDSNILEAIFYTTEGDEFFRTANPNKDMHSVAEKLKAFLDTKPIIGRHQRQLLEETAQVVIKDDKGTAHRMDISTHNPNTLKNNGSGRVGYDEHRGDFRQESPALESPYELEAEFGNSKDGVMLEASTGILLSQVSVDVATRIGRISIGTFNVNCFLYSDWILAPAHLQDRNGAVTIEFPDQTVSTTTDNLNAHGVKRFYGLDLIAIRRPPSLRPEKKLVKAFAITEPVIAQMVFIDSQGIRKFSQSDWIRQEVGSNRWSHKISTQSGMCGCPVLDVGKNRLIGIHVATNHTTGRNEFQPFSREAVDFINGPGNKVPFSPWTFCRPACGYKQGDATFASRTIQTQASDTLSKINNSILGFGSDLKGQLVQPITPALRTRFEALFGGGSFELVGTMNKGLIDKHTIVGENDNVHDFMREHPTFAWLQGFMDEYAPSVLNYSAYYKDLCKYNRKKHQLSFNPHELRSATAGMIRMLEDAGLTQGDVRTPQQVVSDMQWNTSAGPSYQGKKRDVCAHLSEQEVLHLAETSRQQFLACNSIGIWNGSLKAELRTIEKVEAEKTRVFTASPITSLFAMKFYVDDFNKKFYATNLKAPHTVGINKFSRGWEMLHDKLNRPGWLHGSGDGSRFDSSIDPFFFDIIKEIRKHFLPVEHHRAIDLIYDEILNTNICLANGMVIRKNVGNNSGQPSTVVDNTLVLMVSFLYAYIHKTGDHMLKKLNDRFVFVCNGDDNKFAISPEFDAEFGHDFSPELTELGLTYEFDDITDDICANPYMSLTVVRTPFGIGFSLPVERIVAIMQWAKKGGVLHSYLAGISAIYESFNTPKLFKSVYAYLLWLTEEHGSDILAAMTGTATALPIPSMLDVYRLHYGDSSIELQAADTQTDAQKEEARLAAATKKAADDADAARLRKVEADRVEAARVKKASDDKKARDLTATKADDGKIVADAGTKRTNAATKEKWSLPETKPVNAGLKLRISMDKLKSAPKSIVEHDNSIALDSEVRKWSDAVRTSLGITTDEAWINALIPFLGWCANSGASDKHAENQTMQVDNGTGVLTEMSLSPFIVHARLNGGLRRILRAYSDETVLLLQEHKIVTKWAMKHGASAHAAYAFDFFVPRPWMNPQDIEVAKQARLAALGTGTYNTMLTSDTTNLRKTTNRRVLDTDGHPELT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KX258947
EMBL· GenBank· DDBJ
APY27176.1
EMBL· GenBank· DDBJ
Genomic RNA

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