A0A1P8AQ95 · STMP4_ARATH

Function

function

Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (By similarity).
Prevents general growth and development (PubMed:31001913).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapoplast
Cellular Componentplasma membrane
Molecular FunctionLRR domain binding
Molecular Functionreceptor serine/threonine kinase binding
Biological Processresponse to ethylene
Biological Processresponse to jasmonic acid
Biological Processresponse to salicylic acid
Biological Processresponse to salt stress
Biological Processresponse to water deprivation

Names & Taxonomy

Protein names

  • Recommended name
    Secreted transmembrane peptide 4
  • Alternative names
    • Phytocytokine STMP4
    • Precursor of secreted transmembrane peptide 4

Gene names

    • Name
      STMP4
    • ORF names
      F5I14
    • Ordered locus names
      At1g65486

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    A0A1P8AQ95

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
Note: The precursor of STMP4 accumulates at the plasma membrane and is proteolytically cleaved to release the STMP4 in the apoplasm.

Keywords

Phenotypes & Variants

Disruption phenotype

Slightly increased growth and fresh weight.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 24 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for peptide, signal, propeptide.

TypeIDPosition(s)Description
PeptidePRO_0000457263?-97Secreted transmembrane peptide 4
Signal1-33
PropeptidePRO_000045726234-?Removed in mature form

Keywords

Expression

Tissue specificity

Mostly expressed in leaves and stems, and, to a lower extent, in roots, siliques, seeds and flowers.

Induction

Induced by drought, salt stress, jasmonate (MeJA), ethylene (ET) and salicylic acid (SA), mainly in shoots.

Gene expression databases

Interaction

Subunit

Interacts with MIK2 (via extracellular leucine-rich repeat domain); this interaction triggers the formation of complex between MIK2 and the BAK1/SERK3 and SERK4 coreceptors, and subsequent BAK1 activation by phosphorylation.

Family & Domains

Features

Showing features for motif, region.

TypeIDPosition(s)Description
Motif54-67SCOOP motif
Motif60-62SxS motif essential for MIK2 binding
Region75-97Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    97
  • Mass (Da)
    10,464
  • Last updated
    2017-04-12 v1
  • Checksum
    9051E2BD9F81CB24
MTKNMTKKKMGLMSPNIAAFVLPMLLVLFTISSQVEVVESTGRKLSWAFNGAPIVFTPPSSSCGGSPAAVMASEWMPRRPCRRTRPPGTNIPVSQSP

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8AQC5A0A1P8AQC5_ARATHSTMP493
F4IBH0F4IBH0_ARATHSTMP461
B3H5R3B3H5R3_ARATHSTMP488

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC001229
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002684
EMBL· GenBank· DDBJ
ANM58826.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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