A0A1P7Y0C9 · SQS8_PANGI

Function

function

Component of the triterpene saponins (e.g. ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:27746309, PubMed:29378087).
Catalyzes the biosynthesis of squalene (By similarity).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionfarnesyl-diphosphate farnesyltransferase activity
Molecular Functionfarnesyltranstransferase activity
Molecular Functionsqualene synthase activity
Biological Processfarnesyl diphosphate metabolic process
Biological Processisoprenoid biosynthetic process
Biological Processresponse to jasmonic acid
Biological Processresponse to molecule of fungal origin

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Squalene synthase 8
  • EC number
  • Short names
    PgSS8
    ; SQS 8
  • Alternative names
    • FPP:FPP farnesyltransferase SS8
    • Farnesyl-diphosphate farnesyltransferase SS8

Gene names

    • Name
      SS8

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Damaya
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > campanulids > Apiales > Araliaceae > Panax

Accessions

  • Primary accession
    A0A1P7Y0C9

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004469551-391Squalene synthase 8

Expression

Induction

Induced methyl jasmonate (MeJA) in adventitious roots (PubMed:25642758).
Induced by A.niger mycelium-derived elicitor, thus improving ginsenosides production in adventitious roots culture (PubMed:27746309).

Family & Domains

Sequence similarities

Belongs to the phytoene/squalene synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    391
  • Mass (Da)
    44,481
  • Last updated
    2017-04-12 v1
  • Checksum
    0F7F3A563FD87AB1
MGSLGAILKHPDDFYPLLKLKIAARHAEKQIPSEPHWAFCYSMLHKVSRSFGLVIQQLGPQLRDAVCIFYLVLRALDTVEDDTSISTEVKVPIVMAFHCHIYDNDWHFSCGTKEYKVLMDEFHHVSNAFLDLGSSYKEAIEDITMRMGAGMAKFICKEVETIDDYDEYCHYVAGLVGLGLSKLFHASGAEDLATDSLSNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPRQIWSKYVDKLEDLKYEENSAKAVQCLNDMVTDALVHAEDCLKYMSDLRGPAIFRFCAIPQIMAIGTLALCFNNTQVFRGVVKMRRGLTAKVIDQTKTMSDVYGAFFDFSCLLKSKVDNNDPNATKTLSRLEAIQKTCKESGTLSKRFCVFDFPLETIFYRV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KP689318
EMBL· GenBank· DDBJ
AJK30630.1
EMBL· GenBank· DDBJ
mRNA
KP689319
EMBL· GenBank· DDBJ
AJK30631.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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