A0A1P6BWE8 · A0A1P6BWE8_BRUMA
- Proteinalpha-1,2-Mannosidase
- GeneBma-mans-1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids532 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Cofactor
Pathway
Protein modification; protein glycosylation.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 168 | Proton donor | |||
Active site | 301 | ||||
Active site | 412 | Proton donor | |||
Active site | 437 | ||||
Binding site | 523 | Ca2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | Golgi membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | mannose trimming involved in glycoprotein ERAD pathway |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namealpha-1,2-Mannosidase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Brugia
Accessions
- Primary accessionA0A1P6BWE8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 9-26 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 365↔398 | ||||
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length532
- Mass (Da)61,702
- Last updated2017-03-15 v1
- MD5 ChecksumBF7143E16F257B8F2B7A5133220C320F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LN856980 EMBL· GenBank· DDBJ | CDP97216.1 EMBL· GenBank· DDBJ | Genomic DNA |