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A0A1P6BWE8 · A0A1P6BWE8_BRUMA

Function

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Pathway

Protein modification; protein glycosylation.

Features

Showing features for active site, binding site.

153250100150200250300350400450500
Type
IDPosition(s)Description
Active site168Proton donor
Active site301
Active site412Proton donor
Active site437
Binding site523Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular ComponentGolgi membrane
Molecular Functioncalcium ion binding
Molecular Functionmannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Biological Processcarbohydrate metabolic process
Biological Processmannose trimming involved in glycoprotein ERAD pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    alpha-1,2-Mannosidase
  • EC number

Gene names

    • Name
      Bma-mans-1
    • Synonyms
      Bm1_35990
    • ORF names
      BM_Bm3042

Organism names

  • Taxonomic identifier
  • Strain
    • FR3
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Brugia

Accessions

  • Primary accession
    A0A1P6BWE8

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane9-26Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond365↔398

Keywords

Family & Domains

Sequence similarities

Belongs to the glycosyl hydrolase 47 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    532
  • Mass (Da)
    61,702
  • Last updated
    2017-03-15 v1
  • MD5 Checksum
    BF7143E16F257B8F2B7A5133220C320F
MVVRYWRKSVLISVIVFSFLFSLYYLPSSDDSFFRSGRLFQSDRSRFLAQVRQQRFELEERQFDEEPRKVEDESDAISVERCQFIINMTKFAWENYRKYAWGFNELKPLSRSEHSASVFGNGKLGATIVDALDTLYIMGLKEEYEEGRNWVKNFFDLKVSTADISVFETNIRFIGGLLAAYALTEDKMYIQKATNVANILLPAFETPTGIPHALVNPVSGRSHNWAWANGGFSILSEFGSLQLELDYLSQLTQNSIYSTKVARIREIVLSVRTEDGLYPNYLHPKSGKWGPKHVSVGALGDSFYEYLLKSWLRSSKNDTVYKEMYDAALAAIKKYLLRYSSQNHLAYFIELKGKREVHKMDHLACFIVGLLALEALNENDIKRRNDALKLAEEIANTCHESYIRTATGIGPESFRFTKEVEVMAIKDSEKYYILRPEVIEGWFYLWRVTRKNKYREWCWMAAKNIEKYCRTTGGYSGIKNVYSSEVVHDDVQQSFVFAETFKYLYLTFSNDSIMPLNKWVFNTEAHAFPIVT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LN856980
EMBL· GenBank· DDBJ
CDP97216.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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