A0A1N7D7M7 · A0A1N7D7M7_9GAMM

Function

function

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionpenicillin binding
Molecular Functionpeptidoglycan glycosyltransferase activity
Molecular Functionserine-type D-Ala-D-Ala carboxypeptidase activity
Biological Processpeptidoglycan biosynthetic process
Biological Processproteolysis
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Penicillin-binding protein 1A
  • EC number

Gene names

    • ORF names
      SAMN02745664_10155

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 21768
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Moraxella

Accessions

  • Primary accession
    A0A1N7D7M7

Proteomes

Subcellular Location

Cell inner membrane
; Single-pass type II membrane protein

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain69-243Glycosyl transferase family 51
Domain338-428Penicillin-binding protein OB-like
Domain430-753Penicillin-binding protein transpeptidase
Region641-665Disordered
Compositional bias651-665Polar residues

Sequence similarities

In the C-terminal section; belongs to the transpeptidase family.
In the N-terminal section; belongs to the glycosyltransferase 51 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    787
  • Mass (Da)
    86,493
  • Last updated
    2017-03-15 v1
  • MD5 Checksum
    F412B2406D4C807FF347CF9748CD0747
MSNQSFSASFFAILAKLILAILALLAILLLAFPIGFYGMAMYLEPTLPDVKKIDNTKFEMPLQIYTADNKLIGQYGNRYSMPVRFEEIPKPMISAFLAAEDDTFFEHSGISVKGMGRAITEVLTDNDTQTGGSTITMQVAKNYFLSSERTISRKLTELFIARKIESELSKNEILTLYVNKIYLGEGTYGIQAAARRYYSKTLDQLTIAQMAMIAGLPKAPSAYNPVINPDRAMERRNWIIGRMFEEGFISAAERDAAINEPIGLNLYQEKLDLNLPYIAEMARSSLVERFGEAVMDSGWRVQTTVSSSSQLAADQALVGGLRSYDRRHGWRGVEAESGSLDGRKNFDNIYPAKVTKVNNNSFEAQLQSGETVTIGWSGMSWARRYYSANRVGGGYSNANQMVKVGNIVRISPLNEAKTAWKMESIPKVQGALVSLDPTNGALRAVVGGFHFNQSKFNRAIQGYRQPGSIIKPFVYAAALETGKYTPDSMVSDAAIRIGSWRPKNADGRYTGNMTLRRALALSRNTPAIRLMRSAGIDETRSLMNAMGGLEMERMPPTLAVALGAAEATPLQMATGFATIANGGHRVQPYIIERIYDFYSNTIYQANPVQACAVCFNDQLQTTNAKLLETFEANKAKQETLAAAGTPQGDRLQPKTAPQYSTATQAPRVLSQETSYNVSNMMREVVTSGTGRRARALGRGDVGGKTGTTNLAKDAWFAGFHPTNVAVVWVGFDTPSPLGAKEYGGFAALPIWVNFMRQELKGTPSQWVSKEDRSKAIKATQQVVNLTD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias651-665Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FTNU01000001
EMBL· GenBank· DDBJ
SIR71821.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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