A0A1N6XDF9 · A0A1N6XDF9_9EURY
- Protein1,4-dihydroxy-2-naphthoyl-CoA synthase
- GenemenB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids314 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
Catalytic activity
- 2-succinylbenzoyl-CoA + H+ = 1,4-dihydroxy-2-naphthoyl-CoA + H2O
Pathway
Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.
Quinol/quinone metabolism; menaquinone biosynthesis.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 43 | substrate; ligand shared between two neighboring subunits; in other chain | |||
Binding site | 88-92 | substrate; ligand shared between two neighboring subunits; in other chain | |||
Binding site | 100 | substrate; ligand shared between two neighboring subunits; in other chain | |||
Site | 100 | Important for catalysis | |||
Binding site | 157-161 | substrate; ligand shared between two neighboring subunits; in other chain | |||
Binding site | 184 | substrate; ligand shared between two neighboring subunits; in other chain | |||
Site | 185 | Important for catalysis | |||
Binding site | 190 | substrate; ligand shared between two neighboring subunits; in other chain | |||
Binding site | 287 | substrate; ligand shared between two neighboring subunits | |||
Site | 287 | Important for catalysis | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity | |
Biological Process | menaquinone biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name1,4-dihydroxy-2-naphthoyl-CoA synthase
- EC number
- Short namesDHNA-CoA synthase
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Natrialbaceae > Natronorubrum
Accessions
- Primary accessionA0A1N6XDF9
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 96-129 | Disordered | |||
Compositional bias | 102-118 | Basic and acidic residues | |||
Sequence similarities
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length314
- Mass (Da)34,875
- Last updated2017-03-15 v1
- ChecksumA93501C0101E3BEB
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 102-118 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP019327 EMBL· GenBank· DDBJ | APX95982.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FTNP01000001 EMBL· GenBank· DDBJ | SIR00279.1 EMBL· GenBank· DDBJ | Genomic DNA |