A0A1L9V3I6 · A0A1L9V3I6_ASPGL

Function

function

ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
RNA helicase.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleolus
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Biological ProcessrRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase
  • EC number

Gene names

    • ORF names
      ASPGLDRAFT_62494

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 516.65
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Aspergillus

Accessions

  • Primary accession
    A0A1L9V3I6

Proteomes

Organism-specific databases

Subcellular Location

Interaction

Subunit

Component of pre-60S ribosomal complexes.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, motif, region, compositional bias.

TypeIDPosition(s)Description
Domain14-42DEAD-box RNA helicase Q
Motif14-42Q motif
Domain45-248Helicase ATP-binding
Domain282-436Helicase C-terminal
Region530-643Disordered
Compositional bias539-555Polar residues
Compositional bias579-626Basic and acidic residues

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similarities

Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    643
  • Mass (Da)
    71,374
  • Last updated
    2017-03-15 v1
  • Checksum
    2FEE1D5BF5891A46
MAPKPPSGTSARSWDGVNPPLSEWVLEAVSSMGFTRMTPVQASAIPLFMAHKDVVVEAVTGSGKTLSFLIPVVEKLLRVEEPIKKHHVGAIIISPTRELASQIYKVLLSLLEFHPASAAAINPSEDDASRKKQSSSTYKVVPQLLLGGATSPAEDLSNFLKRSPNLLVSTPGRLLELLSSPHVHCPQSSFEMLVLDEADRLLDLGFKNDLQNILRRLPKQRRTGLFSASVSEAVDQIVRVGLRNPVKVIVKVKGSSGALDKRTPASLQMTYLTVPALHKFPALKKILSSVQPTPQKTIFFVSTCTGVDYLAAILPSILGNEYSLIPLHGKHPATVRQKNFNAYVNSQTPAILLTTDVASRGLDIPSVDLVVQLDPPADPKTFIHRCGRAGRAGRRGISVVLLHPGREEDYVSFLEVRKTPVTAFPYPIDITDEDAAAATETARKIALKDRAYHDRGQKAFVSWLRSYSKHQASSIFRVADLDWEGLGKSWGLLKLPKMPELRNFTGDRTLGVKIDWDNYTYKDKQREARRKEALAEYQNGTAEDNQQSNKRPASESVAWSDKLDNKNKKAKRKDQKKAKQDHTKWERMTEEEKQKVLETETMLAEVKKKNDEERRLRREAKKAETGGKGAAGDGVEEEFQGFD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias539-555Polar residues
Compositional bias579-626Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KV878935
EMBL· GenBank· DDBJ
OJJ78487.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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