A0A1L9UD06 · A0A1L9UD06_ASPBC

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site77-84GTP (UniProtKB | ChEBI)
Binding site141-145GTP (UniProtKB | ChEBI)
Binding site195-198GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrial matrix
Cellular ComponentRNA polymerase III complex
Molecular FunctionDNA binding
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionribosome binding
Molecular FunctionRNA polymerase III activity
Biological Processpositive regulation of translation
Biological Processtranslation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit
  • EC number

Gene names

    • ORF names
      ASPBRDRAFT_157463

Organism names

Accessions

  • Primary accession
    A0A1L9UD06

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain68-248Tr-type G
Coiled coil880-907

Sequence similarities

Belongs to the GTP-binding elongation factor family. LepA subfamily.
Belongs to the RNA polymerase beta' chain family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,116
  • Mass (Da)
    236,528
  • Last updated
    2017-03-15 v1
  • Checksum
    F71F5EC4271E2080
MRGCLQLARWLRAAPKCPAASLLKPPSGLANPARFFTTSAACWASRSRGPAGQPASDLESRIAAIPIDRYRNFCIVAHVDHGKSTLSDRLLELTGTIQPGMNKQVLDKLDVERERGITVKAQTCTMIYNHNGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGIQAQTVANFYLAFSQGLELIPVINKVDLPSADPERALDQMEQSFELDTESAVLVSAKTGLNVQQLLPTVVEKIPAPVGDVNNPLRLLLVDSWYDSYRGVICLVRVFDGEIRAGDQLVSFATGIKYFVGEVGIMYPNETPQSVLRAGQVGYIFFNPGMKRSKEAKIGDTYTKVGFEKVVEPLPGFEEPKAMVFVAAYPVDADHFEHLEDSINQLCLNDRSITVQKESSHALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPSVPVKLIWKDGKEEIISNPAKFPEEEELRGKVSEIQEPYVVATLTLPDEYLGKVIELCESNRGVQKSLEYFTSTQVILKYDLPLAQLVDDFFGKLKGSTKGYATLDYEESAWQTSNIVKLQLLVNKAPVDAVARLVHYSQVERLGRQWVTKFKQHVDRQLFEIVIQAAVGRKVVARETVKPYRKDVLAKLHASDVSRRRKLLEKQKEGRKKLRAVGNVSVSPCHDHHLTTAMQPPEGVQVDLGKAQVLDRVPKVIKELKFGVLSNDDIVSQGVVEVSDRKFFDLDHDRAVVANGPLDARMGISNKTSSCQTCGGALQVCNGHFGHVRLVLPAFHVGYFKRVITILQEVCKECSRILLPEADRRAYLREMRRPGLDNLRRGQIAKRINERCRKTRNCEACGAVNGVVKKAGTSALKITHDKFRAFNASTSVKKVPPPSKIVFDRSFDEARTSNAEVEKHYKKAQDDMNALRVLNLFKKISDTDCELLGLNPKEARPEMFLWQFIPAPPVCIRPSVGQDAASTEDDLTAKLGDIVQSNINLKNALLKGAPVQTIMECWDYMQLQIAVYINSDVPGLNKADLGKPIRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRVDEVAVPELVAKNMTYPEVVTRYNKEKLQQRVRNGTKKWPGANYIMKKGQTFKLFLKYGNLNMIADQLQEGDVIERHIEDGDIVLFNRQPSLHKLSILSHFAKVRPHRTFRLNECVCNPYNADFDGDEMNLHVPQTEEARAEAMELMGVKNNLATPKNGEPIISAIQDFISAAYILSSKDNFFDRRSFTQICLYMLGPETRFDLPPPAVLKPQMLWTGKQVFNILMRPNKDDPVLVNLDAACRQFKAPKDGRPRDLDEKDSWLVIRNSEVMCGVMDKSTIGSGKKDNVFYIMLRDYGPVAAAEGMNRLSRLSARWFTNMGFSIGITDVYPSEKLLRSKHDLVETAYAQCDEVIAKYKAGTLEKYPGCDELQTMENQLSGILSKVRQQAGDECIAQLSKYNSPLIMATSGSKGSSINVSQMVALVGQQIIGGQRVQDGFQDRTLPHFPKNARQPPSKGFVRNSFFSGLEPTEFIFHAMSGREGLVDTAVKTAETGYMSRRLMKSLEDLSTRYDDTVRNSSAAIVQFQYGDDKLDPLDMEGKAKPVHFDRTFIHAESTTYKNDERSLLPAEIMEICEEMLSKERSKLVRKDLMGNELGYMDRSDHGIDQFESARDFLESIQQYVATKADKLISRGGDIDPNDERSQKGLNHTGKLTERTLRTFISSCLMKYKKAQVEAGHAVGAVGAQSIGEPGTQMTLKTFHFAGVAGMSITQGVPRIKEIINASKEISTPVVACELVTKDNIIAARIVKGRIEKTYLRDIIHYVRETWTGKEAYITVKINWKTIQDLALELKIENILSAIKNHKRFKADDLKFRCSRSHIHVYMDVDPSTKANLSKTEIAHTSSDPFLRLKHLKRMLPDIQVLGHPQAFRAIIRTDETSTTNTLLVEGYGLRECMTTMGVDGLRTSTNNVMEMRDVLGIEAARTTIVQEISEVMKDMDIDPRHMQLLADVMTYKGEVLGITRFGLAKMRDSVLQLASFEKTADHLFDAGGAGRSDLIEGVSECIIMGKTVSLGTGAMEVVRKMNFFEGQIGARKTTFEDTWTEVYEAPLERAKAARRKRS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KV878688
EMBL· GenBank· DDBJ
OJJ69511.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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