A0A1L8I6W5 · A0A1L8I6W5_9BACI

  • Protein
    Orotidine 5'-phosphate decarboxylase
  • Gene
    pyrF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site12substrate
Binding site33substrate
Active site60For OMPdecase activity
Binding site60-69substrate
Active site62For OMPdecase activity
Active site62Proton donor
Active site65For OMPdecase activity
Binding site123substrate
Binding site185substrate
Binding site198substrate
Binding site218substrate
Binding site219substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Orotidine 5'-phosphate decarboxylase
  • EC number
  • Alternative names
    • OMP decarboxylase
      (OMPDCase
      ; OMPdecase
      )

Gene names

    • Name
      pyrF
    • ORF names
      A6D91_00145

Organism names

Accessions

  • Primary accession
    A0A1L8I6W5

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-234Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    241
  • Mass (Da)
    26,120
  • Last updated
    2017-03-15 v1
  • Checksum
    844CC07D3C030A7D
MSMAERVIIALDFPTAGEALAFLDRVPQVRYVKVGMELFYAAGTTLLEQLKRRGLRIFLDLKLHDIPNTVGRAMAVLAGLGVDMLNVHAAGGREMMLRAKEGVEKGVPAGQPAPRLIAVTQLTSTDQQVLNEELGIPGSVEEAVLRYARLAKQCGLDGVVASPWEVGTIKEACGPAFLCVTPGVRPQAQEDGQRRDDQRRIMTPQEAWQAGSDYLVVGRPVTRASDPAQAFADIVAQLHRP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LWLU01000232
EMBL· GenBank· DDBJ
OJF17456.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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