A0A1L8I6Q3 · A0A1L8I6Q3_9BACI

  • Protein
    Pyridoxal 5'-phosphate synthase subunit PdxS
  • Gene
    pdxS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site25D-ribose 5-phosphate (UniProtKB | ChEBI)
Active site82Schiff-base intermediate with D-ribose 5-phosphate
Binding site154D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site166D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site215D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site236-237D-ribose 5-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Processamino acid metabolic process
Biological Processpyridoxal phosphate biosynthetic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxS
  • EC number
  • Short names
    PLP synthase subunit PdxS
  • Alternative names
    • Pdx1

Gene names

    • Name
      pdxS
    • ORF names
      A6D91_03715

Organism names

Accessions

  • Primary accession
    A0A1L8I6Q3

Proteomes

Interaction

Subunit

In the presence of PdxT, forms a dodecamer of heterodimers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-213PdxS/SNZ N-terminal

Sequence similarities

Belongs to the PdxS/SNZ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    295
  • Mass (Da)
    31,766
  • Last updated
    2017-03-15 v1
  • Checksum
    EA99E76F18263D1B
MTKEQSTWRNKVGLAEMLKGGVIMDVTTPEQAVIAEKAGAVAVMALERVPADIRAQGGVARMSDPKVIKEIMSAVTIPVMAKARIGHFVEAQILEALGVDFIDESEVLTPADEENHIWKHDFKVPFVCGATNLGEALRRIAEGAAMIRSKGEAGTGNVVEAVRHLRSILRDLRRVVNAPIDELQALAKEMRVSLELLQEVKEKGRLPVPLFCAGGVATPADAALVMQLGAEAVFVGSGIFKSGNPEKRARAIVLAVQHYNDPKILAEISEDLGEPMVGINISTIPESERLAGRGW

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LWLU01000244
EMBL· GenBank· DDBJ
OJF17396.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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