A0A1L8G016 · DAA11_XENLA
- ProteinDynein axonemal assembly factor 11
- Genednaaf11
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids469 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Involved in dynein arm assembly, is important for expression and transporting outer dynein arm (ODA) proteins from the cytoplasm to the cilia.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | dynein axonemal particle | |
Cellular Component | extracellular region | |
Cellular Component | motile cilium | |
Biological Process | axonemal dynein complex assembly | |
Biological Process | cerebrospinal fluid circulation | |
Biological Process | epithelial cilium movement involved in determination of left/right asymmetry | |
Biological Process | epithelial cilium movement involved in extracellular fluid movement | |
Biological Process | establishment of localization in cell | |
Biological Process | flagellated sperm motility | |
Biological Process | outer dynein arm assembly | |
Biological Process | protein localization to cilium | |
Biological Process | protein localization to motile cilium |
Names & Taxonomy
Protein names
- Recommended nameDynein axonemal assembly factor 11
- Short namesDNAAF11
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus
Accessions
- Primary accessionA0A1L8G016
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Localized to cytoplasmic puncta in ciliated cells. In the semicircular canal, localized to kinocilia (By similarity).
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000452439 | 1-469 | Dynein axonemal assembly factor 11 | |||
Sequence: MPTISEDLIRRRAEHNNCEIFSLEEISLHQQDLERIEHIDKWCRELKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCESLQKLDLTVNFVGELSSINSLQENLHLRELYLVGNPCAEYEGYRQYVVATLPQLKWLDGKEIERSERIQALQDYPQVQGRMKEQQEAYLRKRAAEREEARSKLQGKQKESRKTQEKKPGFDRRWYTDINNTIPDPVEKPDPTEQNGDETALRKAEEEEEKEFWSQPSQYTPESRLETHRYLEEKRKSKESSSEGELKKKPPRTLITAEGRVLNVNESKLDFSLVDDEENNQFVLDLAIYRHLDTSLVDVDVQPSYIKVLVKEKPFQLVLPAEVKPDSSSAKRSQTTGHLVVTMPKAIGVIQTKRAKSPVVEEQTRKNPPKCSKTFEKLEVDPKACSVPDFANIVQEKKTQAQGPLQFHKNKVKDTEDSEDFIDNTDVPPLM |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for repeat, domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 20-43 | LRR 1 | ||||
Sequence: IFSLEEISLHQQDLERIEHIDKWC | ||||||
Repeat | 44-65 | LRR 2 | ||||
Sequence: RELKILYLQNNLIGKIENVSKL | ||||||
Repeat | 66-89 | LRR 3 | ||||
Sequence: KKLEYLNLALNNIEKIENLEGCES | ||||||
Repeat | 90-110 | LRR 4 | ||||
Sequence: LQKLDLTVNFVGELSSINSLQ | ||||||
Domain | 114-135 | LRRCT | ||||
Sequence: HLRELYLVGNPCAEYEGYRQYV | ||||||
Compositional bias | 179-211 | Basic and acidic residues | ||||
Sequence: KRAAEREEARSKLQGKQKESRKTQEKKPGFDRR | ||||||
Region | 179-290 | Disordered | ||||
Sequence: KRAAEREEARSKLQGKQKESRKTQEKKPGFDRRWYTDINNTIPDPVEKPDPTEQNGDETALRKAEEEEEKEFWSQPSQYTPESRLETHRYLEEKRKSKESSSEGELKKKPPR | ||||||
Compositional bias | 228-251 | Basic and acidic residues | ||||
Sequence: DPTEQNGDETALRKAEEEEEKEFW | ||||||
Compositional bias | 263-290 | Basic and acidic residues | ||||
Sequence: LETHRYLEEKRKSKESSSEGELKKKPPR | ||||||
Region | 436-469 | Disordered | ||||
Sequence: KTQAQGPLQFHKNKVKDTEDSEDFIDNTDVPPLM |
Sequence similarities
Belongs to the tilB family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length469
- Mass (Da)54,340
- Last updated2017-03-15 v1
- Checksum3565B6B4B25C783A
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 179-211 | Basic and acidic residues | ||||
Sequence: KRAAEREEARSKLQGKQKESRKTQEKKPGFDRR | ||||||
Compositional bias | 228-251 | Basic and acidic residues | ||||
Sequence: DPTEQNGDETALRKAEEEEEKEFW | ||||||
Compositional bias | 263-290 | Basic and acidic residues | ||||
Sequence: LETHRYLEEKRKSKESSSEGELKKKPPR |
Keywords
- Technical term