A0A1L8G016 · DAA11_XENLA

Function

function

Involved in dynein arm assembly, is important for expression and transporting outer dynein arm (ODA) proteins from the cytoplasm to the cilia.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentdynein axonemal particle
Cellular Componentextracellular region
Cellular Componentmotile cilium
Biological Processaxonemal dynein complex assembly
Biological Processcerebrospinal fluid circulation
Biological Processepithelial cilium movement involved in determination of left/right asymmetry
Biological Processepithelial cilium movement involved in extracellular fluid movement
Biological Processestablishment of localization in cell
Biological Processflagellated sperm motility
Biological Processouter dynein arm assembly
Biological Processprotein localization to cilium
Biological Processprotein localization to motile cilium

Names & Taxonomy

Protein names

  • Recommended name
    Dynein axonemal assembly factor 11
  • Short names
    DNAAF11
  • Alternative names
    • Leucine-rich repeat-containing protein 6
    • Protein tilB homolog

Gene names

    • Name
      dnaaf11
    • Synonyms
      lrrc6
    • ORF names
      XELAEV_18032374mg

Organism names

  • Taxonomic identifier
  • Strain
    • J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    A0A1L8G016

Proteomes

Organism-specific databases

Subcellular Location

Cytoplasm
Note: Localized to cytoplasmic puncta in ciliated cells. In the semicircular canal, localized to kinocilia (By similarity).

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004524391-469Dynein axonemal assembly factor 11

Proteomic databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for repeat, domain, compositional bias, region.

TypeIDPosition(s)Description
Repeat20-43LRR 1
Repeat44-65LRR 2
Repeat66-89LRR 3
Repeat90-110LRR 4
Domain114-135LRRCT
Compositional bias179-211Basic and acidic residues
Region179-290Disordered
Compositional bias228-251Basic and acidic residues
Compositional bias263-290Basic and acidic residues
Region436-469Disordered

Sequence similarities

Belongs to the tilB family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    469
  • Mass (Da)
    54,340
  • Last updated
    2017-03-15 v1
  • Checksum
    3565B6B4B25C783A
MPTISEDLIRRRAEHNNCEIFSLEEISLHQQDLERIEHIDKWCRELKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCESLQKLDLTVNFVGELSSINSLQENLHLRELYLVGNPCAEYEGYRQYVVATLPQLKWLDGKEIERSERIQALQDYPQVQGRMKEQQEAYLRKRAAEREEARSKLQGKQKESRKTQEKKPGFDRRWYTDINNTIPDPVEKPDPTEQNGDETALRKAEEEEEKEFWSQPSQYTPESRLETHRYLEEKRKSKESSSEGELKKKPPRTLITAEGRVLNVNESKLDFSLVDDEENNQFVLDLAIYRHLDTSLVDVDVQPSYIKVLVKEKPFQLVLPAEVKPDSSSAKRSQTTGHLVVTMPKAIGVIQTKRAKSPVVEEQTRKNPPKCSKTFEKLEVDPKACSVPDFANIVQEKKTQAQGPLQFHKNKVKDTEDSEDFIDNTDVPPLM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias179-211Basic and acidic residues
Compositional bias228-251Basic and acidic residues
Compositional bias263-290Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM004476
EMBL· GenBank· DDBJ
OCT77178.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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