A0A1L8EJF3 · A0A1L8EJF3_HAEIR

Function

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site, site.

1972100200300400500600700800900
TypeIDPosition(s)Description
Binding site396Zn2+ (UniProtKB | ChEBI); catalytic
Active site397Proton acceptor
Binding site400Zn2+ (UniProtKB | ChEBI); catalytic
Binding site419Zn2+ (UniProtKB | ChEBI); catalytic
Site482Transition state stabilizer

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular Functionaminopeptidase activity
Molecular Functionmetallopeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aminopeptidase
  • EC number

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Muscoidea > Muscidae > Haematobia

Accessions

  • Primary accession
    A0A1L8EJF3

Subcellular Location

Cell membrane
; Lipid-anchor, GPI-anchor
Membrane
; Lipid-anchor, GPI-anchor

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias54-85Polar residues
Region54-90Disordered
Domain98-284Aminopeptidase N-like N-terminal
Domain324-542Peptidase M1 membrane alanine aminopeptidase
Domain624-942ERAP1-like C-terminal

Sequence similarities

Belongs to the peptidase M1 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    972
  • Mass (Da)
    111,013
  • Last updated
    2017-03-15 v1
  • Checksum
    32C9C6DE4437EDD1
MLVAGKFVTILLGMALTAFTVSTIVLAVQKSNLKSELQETKDKLELLEEALKTTTTTTTTTTTTSPTTSSSSTSSSTSSPTTADPSEPIDYRLPGNLVPTNYQLYLHPNIETGNFSGQVVISIDCVESTDKIVLHSLYLNINNVYVSNVGSGTNFVKNYELDNVREFLVIEMNEVIAAPRKFQLGIIFEGSMTDKIVGLYSSSYTKPDQTKKWIATSKFEPTYARQAFPCFDEPALKATFEITLVYPNDGGYHALSNMDIAEEQFQDTHTEVHFSKSVPMSTYLACFIVSDFKSKDVKIDTKGIGEEFDMRVFATPEQLDKVDFAVDVGKGVIEYYIDYFQIPYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDEAVSSTANKQRIASVIAHEYAHMWFGNLVTMMWWNDLWLNEGFASYIENKGVEAVYPEWKMRDQFITGTLHGVLSLDATLGSHPIIQTVANPDQITEIFDTITYSKGSSIIRMLEDFLGPENFQHAVTNYLNEFKYKNAVTDDFLTEIEKLNLGFDVKAIMRTWTEQMGLPVVEVQQLSATQYKLTQKRFFSNPQDYEGTYNDSPFDYKWSIPITYKTSASDEVQREWFYYDQNDLTITLPSAVEWIKFNFDQIGYYRVNYPISMWENLADKLIENPNIFSIGDRACLLNDAFSLADATQIEYDLALDMTKYLSKEDQYVPWSVAASKLTSLKRTLMFTDAFVDYNSYSRDLIAPIYESVGWTVGSDHLQNHLRVTILSAACSLGLPACLTKASEEFTKWLENPSVRPHPDVRETIYYYGMFDSGDEKNWNQMWELFVTEEDASEKSKLMYGLSAVQVPWILSRYIQLAWNPDYVRGQDYFTCLQYIAANPVGEPLVWEYVREHWEDLVERFGLNERYLGNMIPSITGRFYTETKYEEMTYFFNKYPDAGAGTAARVRALETVKNNIAWLDNNLALVRDWLSKRNSQMKIINFL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias54-85Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GFDG01000011
EMBL· GenBank· DDBJ
JAV18788.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

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