A0A1L8E887 · A0A1L8E887_HAEIR

Function

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrion
Molecular Functionmalate dehydrogenase (decarboxylating) (NADP+) activity
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Biological Processmalate metabolic process
Biological Processpyruvate metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Malic enzyme

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Muscoidea > Muscidae > Haematobia

Accessions

  • Primary accession
    A0A1L8E887

Subcellular Location

Family & Domains

Features

Showing features for compositional bias, region, coiled coil, domain.

TypeIDPosition(s)Description
Compositional bias1-24Polar residues
Region1-34Disordered
Coiled coil167-201
Domain198-379Malic enzyme N-terminal
Domain389-642Malic enzyme NAD-binding

Sequence similarities

Belongs to the malic enzymes family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    683
  • Mass (Da)
    76,205
  • Last updated
    2017-03-15 v1
  • Checksum
    3DB4F71FA5980308
AEQSPNSVVNPVVVVPNSESSSRVNTDTGKEESIEKTTNYSKLPLLSQVDLHDLMRNVNAINAVNHTLRQSFNLQQQQHHHQKSPLYNLQQQSNFHMDFSSMNGNNSPLKKVPRDRLGLWGTGGDVDVPGNISGLQRLQHKKYNKGLAFSVEERQLLGIQGLLPARVKSEEEQVQHCLLLLDRLENDLDKYMYLNNLAERNERLFYKVLASDVAKMMPLVYTPTVGLACQKFSFIFQYPKGMYITINDKGHVYEVLRNWPETDIRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTQSILEDPLYIGLRQKRTTGQEYDEFIDEFMHAVVRRFGQNCLIQFEDFANANAFRLLEKYRNDFCTFNDDIQGTASVAVAGLLASLKIKNTQLKENKILFFGAGEAALGIANLCLMALMKEGLNEAEAKERIWMVDSKGLIVKNRPAGGLTEHKLHFAQDHAPINTLAEAVETLQPSVLIGAAAIGGAFTKEILQRMAEFNDMPIIFALSNPTSKAECTAEEAYKYTNGKCIFASGSPFDPVEYNGKTFYPGQGNNSYIFPGVALGVLCAGMLTIPEEVFLMSAERLADLCEPEDLERGSLYPPLKKITECSVEIAAYIMEYAYKNGLATVRPEPEDKREFIKSQMYDLHYSSSIPEVYSWNHKL

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias1-24Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GFDG01003841
EMBL· GenBank· DDBJ
JAV14958.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp