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A0A1L7TLB7 · A0A1L7TLB7_FUSMA

Function

function

Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.

Features

Showing features for site, active site.

138850100150200250300350
Type
IDPosition(s)Description
Site169Transition state stabilizer
Active site253Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionS-methyl-5-thioribose-1-phosphate isomerase activity
Biological ProcessL-methionine salvage from methylthioadenosine
Biological ProcessL-methionine salvage from S-adenosylmethionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribose-1-phosphate isomerase
  • EC number
  • Short names
    M1Pi
    ; MTR-1-P isomerase
  • Alternative names
    • S-methyl-5-thioribose-1-phosphate isomerase
    • Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein

Gene names

    • Name
      MRI1
    • ORF names
      FMAN_02318

Organism names

Accessions

  • Primary accession
    A0A1L7TLB7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    388
  • Mass (Da)
    42,044
  • Last updated
    2017-03-15 v1
  • MD5 Checksum
    DCD6C7364873D2E724CF770750556F94
MSSLKAVKYIRGQLQVLDQLRLPHEFHYDDVSNRTEAFDSIAAMRVRGAPAIAIVAALGLAVELHNGSITASTAEDTISQIEEALDYLKESRPTAVDLTNAINQLKSTIRSVGSTATKEQVITAFIEEAEKIFEKDLQTNLSIGDHGAEWLRAQAGASPDQKISVLTHCNTGSLATSGHGTALGIIRTLQSKDLLQHAFCTETRPYNQGSRLTAFELVFENIPSTLITDSMAASLFRNRKQEKNIAAVIVGADRVVRNGDTANKIGTYQLAVLAKHHGIKFIVAAPTTSIDLETETGDGIKIEERKKEELTQVTGAVIKPDGTVDESSKVRVATADQRINVWNPAFDVTPAELIDAVVTEKGAIEKGPDGNFDFSKILPERWAKITGA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FCQH01000010
EMBL· GenBank· DDBJ
CVK99478.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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