A0A1L7SXG5 · A0A1L7SXG5_FUSMA
- ProteinRelated to PAN1-actin-cytoskeleton assembly protein
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1452 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | actin cortical patch | |
Cellular Component | endosome membrane | |
Cellular Component | mating projection tip | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | actin binding | |
Molecular Function | calcium ion binding | |
Biological Process | actin cortical patch assembly | |
Biological Process | endocytosis | |
Biological Process | endosomal transport |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium fujikuroi species complex
Accessions
- Primary accessionA0A1L7SXG5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Endosome membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
Component of the PAN1 actin cytoskeleton-regulatory complex.
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain, coiled coil.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-39 | Polar residues | |||
Region | 1-175 | Disordered | |||
Compositional bias | 50-129 | Polar residues | |||
Domain | 187-276 | EH | |||
Region | 288-320 | Disordered | |||
Compositional bias | 332-364 | Polar residues | |||
Region | 332-368 | Disordered | |||
Domain | 455-544 | EH | |||
Domain | 488-523 | EF-hand | |||
Region | 612-636 | Disordered | |||
Compositional bias | 615-636 | Polar residues | |||
Coiled coil | 710-737 | ||||
Region | 841-864 | Disordered | |||
Compositional bias | 882-910 | Basic and acidic residues | |||
Region | 882-1134 | Disordered | |||
Compositional bias | 914-932 | Polar residues | |||
Compositional bias | 972-1005 | Basic and acidic residues | |||
Compositional bias | 1026-1134 | Basic and acidic residues | |||
Region | 1148-1426 | Disordered | |||
Compositional bias | 1166-1192 | Polar residues | |||
Compositional bias | 1202-1219 | Pro residues | |||
Compositional bias | 1220-1243 | Polar residues | |||
Compositional bias | 1253-1267 | Polar residues | |||
Compositional bias | 1337-1413 | Pro residues | |||
Sequence similarities
Belongs to the PAN1 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,452
- Mass (Da)156,805
- Last updated2017-03-15 v1
- MD5 ChecksumB064EFE7B974713114A8FFFA7830A70B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-39 | Polar residues | |||
Compositional bias | 50-129 | Polar residues | |||
Compositional bias | 332-364 | Polar residues | |||
Compositional bias | 615-636 | Polar residues | |||
Compositional bias | 882-910 | Basic and acidic residues | |||
Compositional bias | 914-932 | Polar residues | |||
Compositional bias | 972-1005 | Basic and acidic residues | |||
Compositional bias | 1026-1134 | Basic and acidic residues | |||
Compositional bias | 1166-1192 | Polar residues | |||
Compositional bias | 1202-1219 | Pro residues | |||
Compositional bias | 1220-1243 | Polar residues | |||
Compositional bias | 1253-1267 | Polar residues | |||
Compositional bias | 1337-1413 | Pro residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FCQH01000003 EMBL· GenBank· DDBJ | CVK89172.1 EMBL· GenBank· DDBJ | Genomic DNA |