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A0A1L7SXG5 · A0A1L7SXG5_FUSMA

Function

function

Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentactin cortical patch
Cellular Componentendosome membrane
Cellular Componentmating projection tip
Cellular Componentnucleus
Cellular Componentplasma membrane
Molecular Functionactin binding
Molecular Functioncalcium ion binding
Biological Processactin cortical patch assembly
Biological Processendocytosis
Biological Processendosomal transport

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Related to PAN1-actin-cytoskeleton assembly protein

Gene names

    • ORF names
      FMAN_04476

Organism names

Accessions

  • Primary accession
    A0A1L7SXG5

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Peripheral membrane protein
Endosome membrane
; Peripheral membrane protein

Keywords

Interaction

Subunit

Component of the PAN1 actin cytoskeleton-regulatory complex.

Family & Domains

Features

Showing features for compositional bias, region, domain, coiled coil.

Type
IDPosition(s)Description
Compositional bias1-39Polar residues
Region1-175Disordered
Compositional bias50-129Polar residues
Domain187-276EH
Region288-320Disordered
Compositional bias332-364Polar residues
Region332-368Disordered
Domain455-544EH
Domain488-523EF-hand
Region612-636Disordered
Compositional bias615-636Polar residues
Coiled coil710-737
Region841-864Disordered
Compositional bias882-910Basic and acidic residues
Region882-1134Disordered
Compositional bias914-932Polar residues
Compositional bias972-1005Basic and acidic residues
Compositional bias1026-1134Basic and acidic residues
Region1148-1426Disordered
Compositional bias1166-1192Polar residues
Compositional bias1202-1219Pro residues
Compositional bias1220-1243Polar residues
Compositional bias1253-1267Polar residues
Compositional bias1337-1413Pro residues

Sequence similarities

Belongs to the PAN1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,452
  • Mass (Da)
    156,805
  • Last updated
    2017-03-15 v1
  • MD5 Checksum
    B064EFE7B974713114A8FFFA7830A70B
MYSNSNAFLGGNSQRPGGQQQQYGGGSFGNLGAGQQPGQPSPFAPQPTGFGQAPLQQQYTGFPMQGQGLQPQQPLQQQFTGFPGQQQQQSQPQQQSFQTGAPAMPSIPPQFQQQQQQQPTSFSVSPQQASGPSNPPPAPMKPQATGFTEMAASFQTGGTTKPRGRRQEKSQPNKIPNIRLSFITAQDQAKFETLFKSAVGEAGMTMSGEKARDLLMRSRLDGDSLSHIWTLADTTRAGQLYFPEFALAMYLCNLKLTGKQLPPVLPENIKNEVSSMVDIISFSIADESAPGASSSSAPDIRTNTATPPTIQQPQPQPHASNAQLLQAQMTGFPGQQTGFGQQQGLQNQQTGFPGMASNPQATGYSGPRPPMPPMPTGFGQSLAPGPAGGMAAPLNAQPTGRPGQWGLVNAPSTGLPNIDALQAQMMPQQGREAGNFTTQGLRGNAVIPWAITKEEKTRYDSLFKAWDGLGKGYIGGDQAIEIFGQSGLEKPDLERVWTLADHGNKGRLDLDEFAVAMHLIYRKLNGYPLPNNLPPELVPPSTRNFSQSIGTLKSMLHDESEFRTKSGAALLPQKTGVSYMKNRSFRGAPAGAVAGRKDATVFKNEDEQFGYRSSARRRVGNNSPRPESPASVASNDDLTLDQLKKKIKEKEVLLDAMDFADEKNHEEDDILDRRDRREAEELYRRIRRIQEDIDSHPDAALASGDSDAERRALKRQLQSLTDKVPELASQVRRTEKAIMDARLELFRIKDAKAHPGSGAPIVGTGPGGTVTESDRLKARAKAMMQQRTAALTGKKVDVGTEDLDAPKRLEEESIKVKNEKESNERMVRDVEESVRDFAHGIEDSLKEGGRDNTSQHEKRRWEDALGVEDEVRDFIFDLQRESRSARVRAQDKRPARASARTEESRPERVASPRVESPVSTSRTATPPAGGSYSSYKTPEERAAFIKQQAEQRMAERLAALGIKAPTKSGETAAQRIERERAERAAKLRQAEEEDARREADRQARLAEEQGIPPPTPEQSKAEAKRPPPPPTRHRGKPEADQEAAKRVEEDAAAKRAEEARLAHEHEQQQRETQQMEEDAKEQEDDLAKEREASEARLKALEEQVRQGKLRKEEEKKRKKAAMAEAKEKEAKLAARRAEIEAARQRELELQRQLEAMEDDDSSSSDEDAGPQQITPQASTPTRSDSQVASQELDKKASPPPAAEAVSSPPPPPPPAVVTSPPSETESKNPFFRMMSQSTEGTPAAAPPAPSATNPFHRMTQNQEGKAPSGPVSRRRADTDDWGSDNDDKDDDSDDERPGGGSAAQLASMLFGTMAPPRPLSAAGRESATASPVAANAVTPVAPPPPPPMPNADSPAPITSPPPPPPPPPMPGSDAPSAPPPPPPMPSVGAPPPPPPPMGGAPPPPPPPGDAPAPASGGGRPAGFLSEIQLGKALKKTTTKDSSAAAVAGRVLD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-39Polar residues
Compositional bias50-129Polar residues
Compositional bias332-364Polar residues
Compositional bias615-636Polar residues
Compositional bias882-910Basic and acidic residues
Compositional bias914-932Polar residues
Compositional bias972-1005Basic and acidic residues
Compositional bias1026-1134Basic and acidic residues
Compositional bias1166-1192Polar residues
Compositional bias1202-1219Pro residues
Compositional bias1220-1243Polar residues
Compositional bias1253-1267Polar residues
Compositional bias1337-1413Pro residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FCQH01000003
EMBL· GenBank· DDBJ
CVK89172.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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