A0A1L7ND27 · A0A1L7ND27_PSEPU

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site230Mg2+ (UniProtKB | ChEBI)
Binding site260Mg2+ (UniProtKB | ChEBI)
Binding site262Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • ORF names
      KF715C_ch27490

Organism names

Accessions

  • Primary accession
    A0A1L7ND27

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-27PH

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    889
  • Mass (Da)
    99,323
  • Last updated
    2017-03-15 v1
  • Checksum
    EA745375598A2E10
MAHSYPLRDEDPQETREWIDSIASVVEVEGRPRAHFLIDQLLDFDVSVHGDFHGRVTTPYVNSIAPERELPYPGDLDIEKRLNAYIRWNALTMVLRAGKHSGVGGHIATYASAAVLYDVGFDHFFRGRTERFAGDMVYIQGHSAPGIYGRAYTEGRLTEEQLDNFRRETDRDGVSSYPHPRLMPEFWQFPTVSMGLGPITAAYQARFMRYLENRGLKEHQGRKVWAFLGDGEMDQPESLAAISLAGREKLDNIIFVVNCNLQRLDGPVRGNGKVIQEFESLYRAAGWNVIKVIWGSGWDALLAKDKTGLLRQRMMECVDGEYQTYKSQNGAYVREHFFGKYPELLDLVSDISDEQIWKLARGGHDPVKVYNAYAAATRQKGRPTVILAKTVKGFGMGEAGEGQNINHQLKKMGAEAVKAFSDRFGLALSDDQLGELPYLRPDEASAEARYLKGRRESLGGYVPARYAQVESLQIPPLSALEGQLKGTGDRSISTTMAFVRILSTLLKDPNIGKLVVPIVPDESRTFGMESLFRQIGIHSHVGQLYIPQDAGTLSYYKESADGQIMQEGLNESGATSSWIAASTSYANHGVMTLPFYIFYSMFGFQRVGDLLWAAGDARARGFLLGATSGRTTLMGEGLQHDDGHSHVMSATVPCCISYDPTYAYELAVIVHDGMRRMYVEQEDIYYYITVLNENYPHPDMPEGVEEGILKGLYRLPLEREVKKDLHVQLMGSGALLPEVIAAAQILERDYGVSSEVWSATSLTEVRREAQQVERWNLLHPMEDPKVPYLTQLLDGHAGPVVVSTDYMKIHADQIRPWVGNRRFVALGTDGFGQSDTREALRRHFEVDRQFVVLAALKALADDGVLGRDVVAKALAEMQIDGEKVDPISV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP015029
EMBL· GenBank· DDBJ
BAW23322.1
EMBL· GenBank· DDBJ
Genomic DNA

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