A0A1L7B6G7 · A0A1L7B6G7_MEGAM
- Proteinnon-specific serine/threonine protein kinase
- GeneIRAK1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids706 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | cellular response to cytokine stimulus | |
Biological Process | innate immune response | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Xenocyprididae > Xenocypridinae > Megalobrama
Accessions
- Primary accessionA0A1L7B6G7
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 190-498 | Protein kinase | ||||
Sequence: FSPCKQIGEGGFGHVYQAVMRNTEFAVKKLKEDSHLDWDVVKESFRTEVEKLSQYRHPNIMDFVGYSIDRQIYCLIYVYMPNGSLEDRLRCEDSNALSWSQRVNVLLGTAKAIQYLHSCSPALIHGDIKSSNILLGDHLEPKLGDFGLARFCRSPSKTPGKTSTVAHTATVRGTLAYLPEEYLKDGQLGVEIDVYSFGVVILEVLTGRQALEVDGQSKTVYLKDLVKEEEDDGRSFSKGKHSRELSYVNAAENICRKHLDPRLMTKDTPTPHGSMEISQMACRCLERRRKKRPPMTEVFKALQDVHSGL | ||||||
Region | 504-529 | Disordered | ||||
Sequence: LTTVRLSPVSSHPSTPEPLRSNDSSL | ||||||
Compositional bias | 620-638 | Polar residues | ||||
Sequence: SSSLEENPSQSSPNEDFSD | ||||||
Region | 620-640 | Disordered | ||||
Sequence: SSSLEENPSQSSPNEDFSDQK | ||||||
Region | 671-706 | Disordered | ||||
Sequence: GDSLYRGMNAQTREPEESDEFASETSGVDMQSPAAV |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusComplete
- Length706
- Mass (Da)79,268
- Last updated2017-03-15 v1
- Checksum0BF1CC0F05D754B6
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 620-638 | Polar residues | ||||
Sequence: SSSLEENPSQSSPNEDFSD |