A0A1L5YAW9 · A0A1L5YAW9_9EUKA

  • Protein
    ATP-dependent zinc metalloprotease FtsH
  • Gene
    ftsH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

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Type
IDPosition(s)Description
Binding site210-217ATP (UniProtKB | ChEBI)
Binding site435Zn2+ (UniProtKB | ChEBI); catalytic
Active site436
Binding site439Zn2+ (UniProtKB | ChEBI); catalytic
Binding site512Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentplastid
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent peptidase activity
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processcell division
Biological Processprotein catabolic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent zinc metalloprotease FtsH
  • EC number

Gene names

    • Name
      ftsH
    • Synonyms
      MYN1_Chr_5
    • ORF names
      PCKR_039
      , PFK_039
      , PMNZ_039
      , PMYN1_Chma5

Encoded on

  • Plastid

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • FK01
    • KR01
    • NZ27
    • MYN1
  • Taxonomic lineage
    Eukaryota > Sar > Rhizaria > Cercozoa > Imbricatea > Silicofilosea > Euglyphida > Paulinellidae > Paulinella

Accessions

  • Primary accession
    A0A1L5YAW9

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane17-35Helical
Transmembrane115-136Helical

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain202-344AAA+ ATPase

Sequence similarities

Belongs to the AAA ATPase family.
In the C-terminal section; belongs to the peptidase M41 family.
In the N-terminal section; belongs to the AAA ATPase family.
In the central section; belongs to the AAA ATPase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    620
  • Mass (Da)
    67,637
  • Last updated
    2017-03-15 v1
  • MD5 Checksum
    026973DC7B99E3886D4009554D44E777
MAVRQDDDNRPNRRFRVINFVLIGFGVLLLCSSFIPNSTAQVPRVPYSLFIRQVTEGAVKRAYITQDQIRYELNTPEVGSPSVLSTTPIFDMDLPQRLEKQGVEFAAAPPKKPNIFVTVLSWIVPPLIFILVLQFFARRSMGNSAQGALSFTKSKARVYIPDEASRVTFADVAGVDEAKAELSEIVDFLKTPERYAEIGARIPKGVLLVGPPGTGKTLLSKAVAGEANVPFFIISGSEFVELFVGAGAARVRDLFDQAKQKAPCIIFIDELDAIGKSRSGSMGVVGGNDEREQTLNQLLTEMDGFAAKDKPVIVLGATNQPEILDAALLRPGRFDRQVLVDRPDLSGRKMILEIYAKKVKLSDNVNLDLIAQATSGFAGADLANLINEAALLAARAYRTSVEQEHLNEAIERVVAGLEKKSRVLQDDEKRIVAYHEVGHAIVGHLMPGGSKVAKISIIPRGMSALGYTLQLPTEERFLNSKEDLEGQIATLLGGRSAEEIIFGAITTGASNDLQRATDIAEQMIGTYGMSETLGPLAYDKQGGGRFLGGNQNMRREVSDATAQAIDKEVRNLIDRGHAKAREILNTNRHLLESIAQQILEKEVIEGDDLKNLLSQCVMPS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KX897545
EMBL· GenBank· DDBJ
APP87844.1
EMBL· GenBank· DDBJ
Genomic DNA
KY124271
EMBL· GenBank· DDBJ
AQX44611.1
EMBL· GenBank· DDBJ
Genomic DNA
MG976688
EMBL· GenBank· DDBJ
AXY63002.1
EMBL· GenBank· DDBJ
Genomic DNA
LC490351
EMBL· GenBank· DDBJ
BBL85818.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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