A0A1L5P3N2 · A0A1L5P3N2_RHIET

  • Protein
    Siroheme synthase 1
  • Gene
    cysG-1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.
Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.

Features

Showing features for active site.

147850100150200250300350400450
TypeIDPosition(s)Description
Active site254Proton acceptor
Active site276Proton donor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionNAD binding
Molecular Functionprecorrin-2 dehydrogenase activity
Molecular Functionsirohydrochlorin ferrochelatase activity
Molecular Functionuroporphyrin-III C-methyltransferase activity
Biological Processcobalamin biosynthetic process
Biological Processmethylation
Biological Processsiroheme biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Siroheme synthase 1
      (EC:4.99.1.4
      )

Gene names

    • Name
      cysG-1
    • ORF names
      AM571_CH01939

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 8C-3
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Rhizobium

Accessions

  • Primary accession
    A0A1L5P3N2

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain157-211Sirohaem synthase dimerisation
Domain223-433Tetrapyrrole methylase

Sequence similarities

Belongs to the precorrin methyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    478
  • Mass (Da)
    51,282
  • Last updated
    2017-03-15 v1
  • Checksum
    BEF135611D92A101
MPSSNEQLSVFPAFFRVEGRIAAVFGNGDEAFAKVRLLLNTRARIVAYADHPKADYHSFLLSNRIEMVRGAFLPEQVDGAALVFAATGNPAEDRAVVEAARRARIPANAVDQPDYCDFLTPALVNRAPVAVAIGTEGAGPVLAQMIRAQVDQLLSPSLGRLADLATSYRRTVEHLLPRGIARRVFWRRFFSGRVADAVANGNLAEARRAANGLLRSAEKVDGRVWLVGAGPGAEDLLTLRAQRVMMEADVIVFDALVPQAIVDMGRRDAERLSVGKRKGCHSKSQEEINDLLVQLGRQGKRVVRLKSGDPLVYGRAGEEMAALRTAGIGYEVVPGITSAFAAAADFELPLTLRGVASSLVFTTGHDLTGDVLPDWASLAVSGATIAVYMGRTVAASVAERLMSAGLPAETTVAVVENASRADRRLLHGILRDLPDLQHRNELTGPVMVIIGDAVAGANFELSEPLVRREATAPEFARS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP017241
EMBL· GenBank· DDBJ
APO74752.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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