A0A1L1SV17 · A0A1L1SV17_MOUSE

  • Protein
    Dynein regulatory complex protein 12
  • Gene
    Ccdc153
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcilium
Cellular Componentcytoplasm
Cellular Componentcytoskeleton

Names & Taxonomy

Protein names

  • Recommended name
    Dynein regulatory complex protein 12

Gene names

    • Name
      Ccdc153

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    A0A1L1SV17

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Component of the nexin-dynein regulatory complex (N-DRC).

Family & Domains

Features

Showing features for compositional bias, region, coiled coil.

TypeIDPosition(s)Description
Compositional bias1-17Basic residues
Region1-30Disordered
Coiled coil38-136

Sequence similarities

Belongs to the DRC12 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    155
  • Mass (Da)
    17,827
  • Last updated
    2017-02-15 v1
  • Checksum
    FE228A963BBA0282
MPPKTKGRGRKAEARKKKKNSSPGVEAEAKHRLVLLEKELLQDRLALQREEARRAKASEDRLKQRLQGLEAELERTQSEGKAIYAEMSRQRQALKEELGTRSKQLEEEVRSLKEQLETCQREAKTAKEEAERALRKQDGTLAQLHAHVADMEAKY

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P0C7Q1DRC12_MOUSEDrc12202
A0A1L1SSU0A0A1L1SSU0_MOUSECcdc153154
A0A1L1STT2A0A1L1STT2_MOUSECcdc153187
A0A1L1SQQ7A0A1L1SQQ7_MOUSECcdc153102
A0A1L1SRN4A0A1L1SRN4_MOUSECcdc153209
A0A1L1SQE9A0A1L1SQE9_MOUSECcdc153172

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias1-17Basic residues
Non-terminal residue155

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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