A0A1J9SBD1 · A0A1J9SBD1_9PEZI
- Protein3'-phosphate/5'-hydroxy nucleic acid ligase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids637 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 272-276 | GMP (UniProtKB | ChEBI) | ||||
Sequence: NHFAE | ||||||
Binding site | 273 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 302 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 407 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 407-408 | GMP (UniProtKB | ChEBI) | ||||
Sequence: HN | ||||||
Active site | 505 | GMP-histidine intermediate | ||||
Sequence: H | ||||||
Binding site | 505-508 | GMP (UniProtKB | ChEBI) | ||||
Sequence: HGAG |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | GTP binding | |
Molecular Function | metal ion binding | |
Molecular Function | RNA ligase (ATP) activity | |
Molecular Function | RNA ligase (GTP) activity | |
Biological Process | RNA processing |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3'-phosphate/5'-hydroxy nucleic acid ligase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Dothideomycetes incertae sedis > Botryosphaeriales > Botryosphaeriaceae > Diplodia
Accessions
- Primary accessionA0A1J9SBD1
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 106-134 | Disordered | ||||
Sequence: TVKASSSSSSSSSSKPEAHDDDSGSSSTN | ||||||
Region | 426-447 | Disordered | ||||
Sequence: GLDTATASPSLSNTNGQQRRRR | ||||||
Compositional bias | 428-445 | Polar residues | ||||
Sequence: DTATASPSLSNTNGQQRR |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length637
- Mass (Da)66,709
- Last updated2017-02-15 v1
- Checksum2BBCB3CD06886894
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 428-445 | Polar residues | ||||
Sequence: DTATASPSLSNTNGQQRR |
Keywords
- Technical term