A0A1J9PH62 · A0A1J9PH62_9BURK

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mg2+ or Mn2+ ion per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site106NADP+ (UniProtKB | ChEBI)
Binding site115substrate
Binding site117substrate
Binding site121substrate
Binding site131substrate
Binding site155substrate
Site162Critical for catalysis
Site232Critical for catalysis
Binding site309Mg2+ (UniProtKB | ChEBI)
Binding site341-347NADP+ (UniProtKB | ChEBI)
Binding site354NADP+ (UniProtKB | ChEBI)
Binding site393NADP+ (UniProtKB | ChEBI)
Binding site397NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionisocitrate dehydrogenase (NADP+) activity
Molecular Functionmagnesium ion binding
Molecular FunctionNAD binding
Biological Processglyoxylate cycle
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isocitrate dehydrogenase [NADP]
  • EC number

Gene names

    • ORF names
      BFF94_25980

Organism names

  • Taxonomic identifier
  • Strain
    • DNA89
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex

Accessions

  • Primary accession
    A0A1J9PH62

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue102N6-succinyllysine
Modified residue115Phosphoserine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain30-414Isopropylmalate dehydrogenase-like

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    418
  • Mass (Da)
    45,947
  • Last updated
    2017-02-15 v1
  • Checksum
    5A882546B871A338
MPYQHIKVPEGGDKITVNKDFSLNVSDQPIIPYIEGDGTGFDITPVMIKVVDAAVAHAYKGKRKIHWMEIFAGEKATKVYGPDVWLPDETLQVLKEYVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVQYFKGVPSPVREPQKIDMVIFRENSEDIYAGIEWAAGSEQAKKVIKFLQDEMGVKKIRFPETSGIGVKPVSTEGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGLFRDAGYALAQKEFGGELIDGGPWMRVKNPRTGNEIVIKDSIADAFLQQILLRPAEYDVIATLNLNGDYISDALAAQVGGIGIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSEILSAEMMLRHLGWTEAADTIIASMEKSILQKRVTYDFARLMEGATQVSCSGFGEVLIENM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MDEQ01000146
EMBL· GenBank· DDBJ
OJD07195.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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