A0A1J0VCM8 · A0A1J0VCM8_9GAMM
- ProteinCell division protein FtsZ
- GeneftsZ
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids390 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 22-26 | GTP (UniProtKB | ChEBI) | |||
Binding site | 109-111 | GTP (UniProtKB | ChEBI) | |||
Binding site | 140 | GTP (UniProtKB | ChEBI) | |||
Binding site | 144 | GTP (UniProtKB | ChEBI) | |||
Binding site | 188 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell division site | |
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Biological Process | division septum assembly | |
Biological Process | FtsZ-dependent cytokinesis | |
Biological Process | protein polymerization |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCell division protein FtsZ
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Oceanospirillales > Halomonadaceae > Halomonas
Accessions
- Primary accessionA0A1J0VCM8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.
Keywords
- Cellular component
Interaction
Subunit
Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 14-206 | Tubulin/FtsZ GTPase | |||
Domain | 208-326 | Tubulin/FtsZ 2-layer sandwich | |||
Region | 320-390 | Disordered | |||
Compositional bias | 362-383 | Basic and acidic residues | |||
Sequence similarities
Belongs to the FtsZ family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length390
- Mass (Da)40,558
- Last updated2017-02-15 v1
- ChecksumD549280B6BA345B8
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 362-383 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP018139 EMBL· GenBank· DDBJ | APE29785.1 EMBL· GenBank· DDBJ | Genomic DNA |