A0A1I9XV56 · A0A1I9XV56_9BURK
- ProteinTriosephosphate isomerase
- GenetpiA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids238 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Catalytic activity
- D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Carbohydrate metabolism; erythritol degradation.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 83 | Electrophile | ||||
Sequence: H | ||||||
Active site | 155 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 161 | substrate | ||||
Sequence: G | ||||||
Binding site | 200 | substrate | ||||
Sequence: S | ||||||
Binding site | 221-222 | substrate | ||||
Sequence: GG |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | triose-phosphate isomerase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glyceraldehyde-3-phosphate biosynthetic process | |
Biological Process | glycerol catabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriosephosphate isomerase
- EC number
- Short namesTIM ; TPI
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Oxalobacteraceae > Janthinobacterium
Accessions
- Primary accessionA0A1I9XV56
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MNGSRTSNAVLLSEIVAGLAASGAASA | ||||||
Chain | PRO_5009606497 | 28-238 | Triosephosphate isomerase | |||
Sequence: VCVPAPYLAQCQAQLAGSALAWGGQDVSAHAGGAYTGEISTAMLQDFGCSYVVIGHSERRAYHGESDAQVAAKTVAALAAGITPIVCIGETLAQREAGQTDAVVAQQLGAVLAAIGADDVARLVLAYEPVWAIGTGKTATPQMAQDVHLVLRGQLAEKNAVAAAGVQILYGGSMKPENAKELMAMPDIDGGLIGGAALKAADFLAIIHAAD |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length238
- Mass (Da)23,865
- Last updated2017-02-15 v1
- Checksum13ACFA282A01F652
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP011319 EMBL· GenBank· DDBJ | APA67648.1 EMBL· GenBank· DDBJ | Genomic DNA |