A0A1H8D7H7 · A0A1H8D7H7_9SPHI
- ProteinDNA ligase (ATP)
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids964 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
Cofactor
Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Probably binds two magnesium or manganese ions per subunit.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 34 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 106 | ||||
Active site | 147 | Proton donor/acceptor | |||
Binding site | 147 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 149 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 149 | Transition state stabilizer | |||
Site | 218 | Important for catalytic activity | |||
Binding site | 247 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 248 | Proton acceptor | |||
Binding site | 248 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 248 | Interaction with DNA substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA ligase (ATP) activity | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | |
Molecular Function | endonuclease activity | |
Molecular Function | metal ion binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA ligase (ATP)
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Sphingobacteriia > Sphingobacteriales > Sphingobacteriaceae > Mucilaginibacter
Accessions
- Primary accessionA0A1H8D7H7
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length964
- Mass (Da)109,578
- Last updated2017-11-22 v1
- MD5 Checksum4D0B138A11E0A2C21E71E363E788584D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FOCL01000002 EMBL· GenBank· DDBJ | SEN03273.1 EMBL· GenBank· DDBJ | Genomic DNA |