A0A1H6QFJ2 · A0A1H6QFJ2_9FIRM

  • Protein
    Multifunctional fusion protein
  • Gene
    msrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site10
Active site284Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine:thioredoxin-disulfide S-oxidoreductase activity
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Molecular Functionpeptide-methionine (S)-S-oxide reductase activity
Biological Processprotein modification process
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Peptide methionine sulfoxide reductase MsrA
  • EC number
  • Short names
    Protein-methionine-S-oxide reductase
  • Alternative names
    • Peptide-methionine (S)-S-oxide reductase
      (Peptide Met(O) reductase
      )
  • Recommended name
    Peptide methionine sulfoxide reductase MsrB
  • EC number
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      msrA
    • Synonyms
      msrB
    • ORF names
      SAMN04487834_100373

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 20406
  • Taxonomic lineage
    Bacteria > Bacillati > Bacillota > Erysipelotrichia > Erysipelotrichales > Coprobacillaceae > Sharpea

Accessions

  • Primary accession
    A0A1H6QFJ2

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain172-295MsrB

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    311
  • Mass (Da)
    35,599
  • Last updated
    2017-04-12 v1
  • MD5 Checksum
    DCD32FB6B58E00CF7214CA2F2830FFD1
MKTIYLAGGCFWGVQKYFDQFDGVISTEVGYANGPEEAPSYEEVCRSSGHAETVKVEYDESKITLTELLKYYFLVVDPTSVNKQGNDVGIQYRTGIYYTTENQLLEAQKVYQAEEQNVGQKLKVELEPLRNFYSAEQYHQKYLKKNPSGYCHIPQKMFNLGKSNSKSKKESPEELEERIGKLAYEVTQHSATERAFTGKYDHFFEKGLYVDVVSGEPLFTSKDKYDSGCGWPAFTKPIKEETLKNKMDFSHLMIRTEVRSAGANSHLGHVFKDGPKDKGGLRYCINSAALRFIPYDDMEKEGYGEYKKYID

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FNYK01000003
EMBL· GenBank· DDBJ
SEI42438.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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