A0A1H2RSM6 · A0A1H2RSM6_9PSEU
- Protein3-phosphoshikimate 1-carboxyvinyltransferase
- GenearoA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids429 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
Catalytic activity
- 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphateThis reaction proceeds in the forward direction.
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 26 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 26 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 27 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 31 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 100 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 128 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 174 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 175 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 176 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 176 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 203 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Active site | 317 | Proton acceptor | |||
Binding site | 317 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 344 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 348 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 389 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 414 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | 3-phosphoshikimate 1-carboxyvinyltransferase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-phosphoshikimate 1-carboxyvinyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Amycolatopsis
Accessions
- Primary accessionA0A1H2RSM6
Proteomes
Subcellular Location
Interaction
Structure
Sequence
- Sequence statusComplete
- Length429
- Mass (Da)44,435
- Last updated2017-11-22 v1
- Checksum85B68399BF81B8F1
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FNON01000001 EMBL· GenBank· DDBJ | SDW22472.1 EMBL· GenBank· DDBJ | Genomic DNA |