A0A1H2RSM6 · A0A1H2RSM6_9PSEU

  • Protein
    3-phosphoshikimate 1-carboxyvinyltransferase
  • Gene
    aroA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site263-phosphoshikimate (UniProtKB | ChEBI)
Binding site26phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site273-phosphoshikimate (UniProtKB | ChEBI)
Binding site313-phosphoshikimate (UniProtKB | ChEBI)
Binding site100phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site128phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site1743-phosphoshikimate (UniProtKB | ChEBI)
Binding site1753-phosphoshikimate (UniProtKB | ChEBI)
Binding site1763-phosphoshikimate (UniProtKB | ChEBI)
Binding site176phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site2033-phosphoshikimate (UniProtKB | ChEBI)
Active site317Proton acceptor
Binding site3173-phosphoshikimate (UniProtKB | ChEBI)
Binding site3443-phosphoshikimate (UniProtKB | ChEBI)
Binding site348phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site389phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site414phosphoenolpyruvate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-phosphoshikimate 1-carboxyvinyltransferase activity
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-phosphoshikimate 1-carboxyvinyltransferase
  • EC number
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate synthase
      (EPSP synthase
      ; EPSPS
      )

Gene names

    • Name
      aroA
    • ORF names
      SAMN05421504_10112

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CPCC 202699
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Amycolatopsis

Accessions

  • Primary accession
    A0A1H2RSM6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-422Enolpyruvate transferase

Sequence similarities

Belongs to the EPSP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    429
  • Mass (Da)
    44,435
  • Last updated
    2017-11-22 v1
  • Checksum
    85B68399BF81B8F1
MTDEDSWTAPVAEAPLDAVVRVPGSKSITNRAYVLSALATAPTRVRAPLDSRDARLMLGALAALGARSEETPGGGYLVHPLNPARIHVEETVNVVLGNAGTVARFTPALATLGSSPVLFDGDEAIRRRPIGPLLQALRDLGADIDDDGRAAPPFTVRGHGGLPGGRVDLDSSASSQFLSALLLAAPATEKGVTVRLVGGNPPSEPHIAMTLDMLRRFGATVDRDGVEFHVPPARLSCPVYTVEPDLSTAAPFVVAPLLTGGKVRIEGWPSSTTQPGDYLRGLVTQLGASVSLDEGGLTVEGGGSFSGATLDLHEVGELTPVIASLLCFADSPSVITGVAHLRGHETDRLAALAAELSGLGADVKDTEDGLRITPAPMTAGVFHTYDDHRLVMAGAVLGLRIPGIDVENPATVGKTFPGFVDAWSSMVTA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FNON01000001
EMBL· GenBank· DDBJ
SDW22472.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help