A0A1G3C2J5 · A0A1G3C2J5_9BACT
- ProteinTyrosine--tRNA ligase
- GenetyrS
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids402 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Catalytic activity
- ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H+ + L-tyrosyl-tRNA(Tyr)
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | RNA binding | |
Molecular Function | tyrosine-tRNA ligase activity | |
Biological Process | tyrosyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTyrosine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Planctomycetota
Accessions
- Primary accessionA0A1G3C2J5
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for motif, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 231-235 | 'KMSKS' region | ||||
Sequence: KMSKS | ||||||
Domain | 340-398 | RNA-binding S4 | ||||
Sequence: IWIVRLLVLSGFAATNGEARRLISQGGVSINNNVLTDPACEVEMETDMILRVGKRRFAR |
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length402
- Mass (Da)46,011
- Last updated2017-02-15 v1
- ChecksumB6B0EE7A5FD54886