A0A1G2ZYD0 · A0A1G2ZYD0_9BACT

Function

function

Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; NAD+ from deamido-NAD+ (ammonia route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site32-39ATP (UniProtKB | ChEBI)
Binding site38Mg2+ (UniProtKB | ChEBI)
Binding site168deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain
Binding site188ATP (UniProtKB | ChEBI)
Binding site193Mg2+ (UniProtKB | ChEBI)
Binding site201deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain
Binding site208deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits
Binding site217ATP (UniProtKB | ChEBI)
Binding site239ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionglutaminase activity
Molecular Functionmetal ion binding
Molecular FunctionNAD+ synthase (glutamine-hydrolyzing) activity
Molecular FunctionNAD+ synthase activity
Biological ProcessNAD biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NH(3)-dependent NAD(+) synthetase
  • EC number

Gene names

    • Name
      nadE
    • ORF names
      A2W31_09730

Organism names

Accessions

  • Primary accession
    A0A1G2ZYD0

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-96NAD/GMP synthase
Domain158-295NAD/GMP synthase

Sequence similarities

Belongs to the NAD synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    325
  • Mass (Da)
    35,773
  • Last updated
    2017-02-15 v1
  • MD5 Checksum
    32B6BFADFB5C17CA178ABE5A83640BA9
MDLDPAAEARRIGAALHQQVFHDLRRKGVVLGISGGIDSSVTAALCVRALGARRVVGVLMPEHDSAPSSLELGRQLADHLGIETVVEDVAGILEAAGCYRRRDDALRRLVPAYGPGYKSKIVLPDLSQGVGYRIFSVVIQAPDGQLFRQRMPLDVYQEVVAATNFKQRVRKMMEYYHADRLRFAVAGTPNLLEFDQGFFVKNGDGAADVKPIAHLYKRQVYQLAAYLGIPAIIRTRPPTTDTYSLEQTQQEFFFSLPWDQMDVCLYGRNHGIPVDQIAAAVGLAPDHVERVYRDIDAKRQAARYLHQGPCLVSGPVPTGGEHAAG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MHYM01000325
EMBL· GenBank· DDBJ
OHB75744.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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