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A0A1G2X651 · A0A1G2X651_9BACT

Function

function

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site825-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site82anthranilate 1 (UniProtKB | ChEBI)
Binding site905-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site92-955-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site94Mg2+ 1 (UniProtKB | ChEBI)
Binding site110-1185-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site113anthranilate 1 (UniProtKB | ChEBI)
Binding site1225-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site168anthranilate 2 (UniProtKB | ChEBI)
Binding site226Mg2+ 2 (UniProtKB | ChEBI)
Binding site227Mg2+ 2 (UniProtKB | ChEBI)
Binding site227Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionanthranilate phosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anthranilate phosphoribosyltransferase
  • EC number

Gene names

    • Name
      trpD
    • ORF names
      A2Y13_01590

Organism names

Accessions

  • Primary accession
    A0A1G2X651

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-67Glycosyl transferase family 3 N-terminal
Domain76-325Glycosyl transferase family 3

Sequence similarities

Belongs to the anthranilate phosphoribosyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    339
  • Mass (Da)
    36,256
  • Last updated
    2017-02-15 v1
  • MD5 Checksum
    41FE34813DE53D63EC064EA9ACB552B7
MTKITEYLEILLEGGSLKYEQAKDLLDTIFKGDVAEVQIAAFLAAMRMKKAMPAEFAGLAQSLRNHAVKINIKPDHLIDTCGTGGAHLKTFNVSTIAAFVAAGAGARVAKHGNRAITSKCGSADVLEALGVKIDCSPDAVVECIEKAGIGFMYAPMYHPAMKFVQPIRKSLDFRTAFNILGPLANPAGVKSQFMGVAEESLLDRIADTLKLLGAKRAMIVHGNGLDEISTTATTKVIELKDNKKISYEIHPADFGLESPKMAELVGSNTEYNANLAKDILYGRKKGPARDIVLLNAAAAIMVADLADNLHQGLTKADEAITSGAAVQCLEKMIEISNKK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MHXU01000178
EMBL· GenBank· DDBJ
OHB41645.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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