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A0A1F5C617 · A0A1F5C617_9BACT

Function

function

Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site192Mg2+ (UniProtKB | ChEBI)
Binding site252Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionmetal ion binding
Molecular Functionphospho-N-acetylmuramoyl-pentapeptide-transferase activity
Molecular FunctionUDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospho-N-acetylmuramoyl-pentapeptide-transferase
  • EC number
  • Alternative names
    • UDP-MurNAc-pentapeptide phosphotransferase

Gene names

    • Name
      mraY
    • ORF names
      A3A25_00975

Organism names

Accessions

  • Primary accession
    A0A1F5C617

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-33Helical
Transmembrane65-85Helical
Transmembrane105-127Helical
Transmembrane139-155Helical
Transmembrane175-192Helical
Transmembrane199-218Helical
Transmembrane224-244Helical
Transmembrane256-284Helical
Transmembrane325-344Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    350
  • Mass (Da)
    38,179
  • Last updated
    2017-02-15 v1
  • MD5 Checksum
    A791E2F857F5AFBF1FFB91767304D897
MIITSEIIRILILTSVAFIVAMAMTPFLTHFLFRYRMGKQIRTEGAPIFAKMHSHKEGTPTMGGILVWLTALILALLFGLLAQIAPDSYLAELNFLSRGQTYLPLGMLIFAALIGMADDVLGIMRIGPKGGGLQMRHRLILYTVAAAVGAWWFYFKLDWDLLHVPFAGDFNVGVWYVPIFIFIIVASAFSTNQTDGLDGLAGGVLLIAFGALAVIAFSQGRMDLAAFCGAIIGALLAFLWFNIYPAKFFMGDTGSMSLGVTLGVIAMLTNSVLILPFIGAVLVLESATTIIQMVSKRLFGKKIFISAPIHHHFEALNWPETKVTMRFWIIAGVAAAIGLIIVFIDKSLVV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MEYT01000045
EMBL· GenBank· DDBJ
OGD38294.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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