A0A1F2Y1U3 · A0A1F2Y1U3_9BACL
- ProteinNAD kinase
- GenenadK
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids282 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Catalytic activity
- NAD+ + ATP = ADP + NADP+ + H+
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 64 | Proton acceptor | |||
Binding site | 64-65 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 138-139 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 149 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 168 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 179-184 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 238 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Molecular Function | NAD+ kinase activity | |
Biological Process | NAD metabolic process | |
Biological Process | NADP biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD kinase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Alicyclobacillaceae > Alicyclobacillus
Accessions
- Primary accessionA0A1F2Y1U3
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length282
- Mass (Da)30,664
- Last updated2017-02-15 v1
- Checksum781538AFD256CB6E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MELW01000323 EMBL· GenBank· DDBJ | OFW75342.1 EMBL· GenBank· DDBJ | Genomic DNA |