A0A1F2Y1U3 · A0A1F2Y1U3_9BACL

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site64Proton acceptor
Binding site64-65NAD+ (UniProtKB | ChEBI)
Binding site138-139NAD+ (UniProtKB | ChEBI)
Binding site149NAD+ (UniProtKB | ChEBI)
Binding site168NAD+ (UniProtKB | ChEBI)
Binding site179-184NAD+ (UniProtKB | ChEBI)
Binding site238NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • ORF names
      A2201_02445

Organism names

Accessions

  • Primary accession
    A0A1F2Y1U3

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    282
  • Mass (Da)
    30,664
  • Last updated
    2017-02-15 v1
  • Checksum
    781538AFD256CB6E
MRTVLLLMNPDKPRAHEVKVRLERRLAQAGFRTICAHTGKDVSGHELADEDLSAAELAFVLGGDGTLLGAARQLAAHGVPLLGMNIGHLGFLSEAEPTTMEETVRRVVHKEYDLESRLMLEATVWRNGEQIAQLIGLNDVGIAKGSFARMVTVDAYVDNVFVDTYSGDGVIVSTPTGSTAYSLSCGGPIVIPHLQVILLTPICPHTLFSRPCVIDDEQVVRLVVHATHDDLGLTVDGQVGVRLLADDVVVVRKSSVQTILVKWRDREFFAVLRQKLHGPGPL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MELW01000323
EMBL· GenBank· DDBJ
OFW75342.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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