A0A1F2P2U1 · A0A1F2P2U1_9EURY

Function

function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N2-acetylornithine and glutamate.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N2-acetyl-L-ornithine (cyclic): step 1/1.
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 1/4.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site2substrate
Binding site27substrate
Site37-38Cleavage; by autolysis
Active site38Nucleophile
Binding site38substrate
Binding site117substrate
Binding site244substrate
Binding site249substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglutamate N-acetyltransferase activity
Molecular FunctionL-glutamate N-acetyltransferase activity
Biological Processarginine biosynthetic process
Biological Processornithine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Including 2 domains:

  • Recommended name
    Glutamate N-acetyltransferase
  • EC number
  • Alternative names
    • Ornithine acetyltransferase
      (OATase
      )
    • Ornithine transacetylase
  • Recommended name
    Amino-acid acetyltransferase
  • EC number
  • Alternative names
    • N-acetylglutamate synthase
      (AGSase
      )

Gene names

    • Name
      argJ
    • ORF names
      SBU_001604

Organism names

  • Taxonomic identifier
  • Strain
    • BOX1
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanosarcinales > Methanosarcinales incertae sedis > ANME-2 cluster > Candidatus Syntrophoarchaeum

Accessions

  • Primary accession
    A0A1F2P2U1

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50234642131-37Arginine biosynthesis bifunctional protein ArgJ alpha chain
ChainPRO_502346421438-249Arginine biosynthesis bifunctional protein ArgJ beta chain

Keywords

Interaction

Subunit

Heterotetramer of two alpha and two beta chains.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the ArgJ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    26,714
  • Last updated
    2017-01-18 v1
  • Checksum
    C3E0567ED9C48C01
MTTDTYPKEVAVEIKGSRRFVIGGVAKGAGMIAPDMATMLAFIYTDASFDSETLQDALRMAVDRSFNMTIVDGDMSTNDMVILTSTGKRSGLRMEEFQEGLNCVCEHLARMIASDGEGATRLIEVLVKGAETKDDAVKAVKTILRSPLVKTAIFGGDPNWGRIACAIGYSGASVSEKKLSISISDGRNEADLLSCGRALDEAVTDLASEILKGETIRIIVDLGLGGEEAKGWGCDLSYEYVRINAEYTS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LYOR01000016
EMBL· GenBank· DDBJ
OFV65478.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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