A0A1E7TXD8 · A0A1E7TXD8_9BURK
- ProteinPeptidoglycan D,D-transpeptidase MrdA
- GenemrdA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids665 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes cross-linking of the peptidoglycan cell wall.
Catalytic activity
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 329 | Acyl-ester intermediate | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | penicillin binding | |
Molecular Function | serine-type D-Ala-D-Ala carboxypeptidase activity | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | proteolysis | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptidoglycan D,D-transpeptidase MrdA
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Variovorax
Accessions
- Primary accessionA0A1E7TXD8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Single-pass membrane protein
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 18-38 | Helical | ||||
Sequence: VIVIGLAVLFAFSLLGSRLVY |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 62-237 | Penicillin-binding protein dimerisation | ||||
Sequence: VPNRGLILDRNGIVLASNYSAYTLEITPSKVGDVEETINSLTSVLEVSPRDRRRFKRLREDSRSFDSIPIRTRLSDEEVARFAAQRYRFPGVEIKARLFRNYPQGELASHVLGYIGRINQREKTAMEDWDEEDQANYKGTDYIGKLGIEQSYEKMLHGQTGVEQMETSAGGRAVRR | ||||||
Domain | 270-608 | Penicillin-binding protein transpeptidase | ||||
Sequence: GALVAIDPKTGEVLAFVSKPTFDPNLFVEGIDTESWQALTESIDKPLLNRALRGTYPPGSTYKPFMALAALQTGKRAASVVVNDPGYFNFGGHRFGSPEGYLGGVDMRRSIQVSSNIYYYSLANEMGVDLIHDFMKPMGFGQITGIDLGGEVRGVLPSTEWKRNAYKRPEQKKWYAGETISLGIGQGYNAFTMLQLAQATAIVADGGMKHRPHLALAMRNTVSGQVVPLPQPPAENLGYTAANVAVIREGLTSVVTSGTARGVFAGAGYQAAGKTGTAQAVTQAKNTKYNARALEEHQRDHALFMAYAPANNPKIALAVIVENAGWGAGAAAPLARRVF |
Sequence similarities
Belongs to the transpeptidase family. MrdA subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length665
- Mass (Da)72,309
- Last updated2017-01-18 v1
- Checksum4E54DCE4FFC043C3
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP023284 EMBL· GenBank· DDBJ | ATA52075.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAUSRS010000002 EMBL· GenBank· DDBJ | MDP9876641.1 EMBL· GenBank· DDBJ | Genomic DNA |