A0A1E7TV51 · A0A1E7TV51_9BURK

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site9-16ATP (UniProtKB | ChEBI)
Binding site99substrate
Binding site106-109substrate
Active site108Proton acceptor
Binding site136ATP (UniProtKB | ChEBI)
Binding site186substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      CKY39_30480
      , J2W25_006189

Organism names

  • Taxonomic identifier
  • Strains
    • J1
    • DS2795
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Variovorax

Accessions

  • Primary accession
    A0A1E7TV51

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    261
  • Mass (Da)
    27,385
  • Last updated
    2017-01-18 v1
  • Checksum
    2739897F61CC1FE2
MSSPFLAIDIGNTRLKWALYEGAFPGAALQAHGAEFLDHIERLADGPWAELPAPGSMLGCVVAGDTLRRRAEEQITERFDCAPRWVVSSAGEAGIVNGYDHPTRLGADRFVAMIGARHRMLSQGPERPMVVVLIGTAVTVEAIDASGKFLGGLILPGHGIMLRALESGTAGLHVPTGEVREFPTNTSDALTSGGTYAIAGAVERMVQHVRSHCGAEPACFMTGGAGWKMAPAMNGDFELVESLIMDGLLVIAKARAPAAAG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP023284
EMBL· GenBank· DDBJ
ATA57068.1
EMBL· GenBank· DDBJ
Genomic DNA
JAUSRR010000014
EMBL· GenBank· DDBJ
MDP9927138.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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