A0A1E7Q1U0 · A0A1E7Q1U0_9GAMM
- ProteinType III pantothenate kinase
- GenecoaX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids231 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
Catalytic activity
- (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H+
Cofactor
Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )
Note: A monovalent cation. Ammonium or potassium.
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 6-13 | ATP (UniProtKB | ChEBI) | |||
Binding site | 82 | substrate | |||
Binding site | 89-92 | substrate | |||
Active site | 91 | Proton acceptor | |||
Binding site | 112 | K+ (UniProtKB | ChEBI) | |||
Binding site | 115 | ATP (UniProtKB | ChEBI) | |||
Binding site | 167 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | pantothenate kinase activity | |
Biological Process | coenzyme A biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameType III pantothenate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Chromatiales > Chromatiaceae > Rheinheimera
Accessions
- Primary accessionA0A1E7Q1U0
Proteomes
Subcellular Location
Interaction
Structure
Sequence
- Sequence statusComplete
- Length231
- Mass (Da)25,065
- Last updated2017-01-18 v1
- Checksum72D74A7F91CC55F5
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MKEK01000001 EMBL· GenBank· DDBJ | OEY68165.1 EMBL· GenBank· DDBJ | Genomic DNA |