A0A1E7Q1U0 · A0A1E7Q1U0_9GAMM

  • Protein
    Type III pantothenate kinase
  • Gene
    coaX
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site82substrate
Binding site89-92substrate
Active site91Proton acceptor
Binding site112K+ (UniProtKB | ChEBI)
Binding site115ATP (UniProtKB | ChEBI)
Binding site167substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      BI198_00250

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KH87
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Chromatiales > Chromatiaceae > Rheinheimera

Accessions

  • Primary accession
    A0A1E7Q1U0

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    231
  • Mass (Da)
    25,065
  • Last updated
    2017-01-18 v1
  • Checksum
    72D74A7F91CC55F5
MYLLLDIGNTRCKAALYENGSLRLVQDLATMDINPTDIEAVIVASVAADEQLQVLKQKLKLTDVRWIQVQSEAAAFGIRNSYSEPEKLGVDRWLAMIAAKQQLPNHSIMVIDAGTAVTIDWLDPQGSHQGGWIIPGLAMQQRAVVSNTAKVLNANEFKPVLAPANNTATALQSGCLAAVIGAIQLAWQNHPTQQIILTGGDSLLLASHLDSLPIIIEPLLVFHGLSRYCRL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MKEK01000001
EMBL· GenBank· DDBJ
OEY68165.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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