A0A1E5SWP8 · A0A1E5SWP8_9BACT

  • Protein
    Uridylate kinase
  • Gene
    pyrH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site9-12ATP (UniProtKB | ChEBI)
Binding site51UMP (UniProtKB | ChEBI)
Binding site52ATP (UniProtKB | ChEBI)
Binding site56ATP (UniProtKB | ChEBI)
Binding site71UMP (UniProtKB | ChEBI)
Binding site132-139UMP (UniProtKB | ChEBI)
Binding site159ATP (UniProtKB | ChEBI)
Binding site165ATP (UniProtKB | ChEBI)
Binding site168ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      BFP97_19290

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 4D4
  • Taxonomic lineage
    Bacteria > Bacteroidota > Cytophagia > Cytophagales > Roseivirgaceae > Roseivirga

Accessions

  • Primary accession
    A0A1E5SWP8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-213Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    235
  • Mass (Da)
    25,918
  • Last updated
    2017-01-18 v1
  • Checksum
    9F0BE23599ED9058
MGYKRVLLKLSGEALMGEQNYGIDSARLEQYALDIKKIHDSGVEIAIVIGGGNIYRGVQAEASGIDRVQGDYMGMLATVINAMAIQSTLEKHGMYTRLMSGIKMEAVCEPFIRRRAVRHLEKGRIVIFGAGIGNPYFTTDSTASLRAIEVEADVVLKGTRVDGVYSADPEKDPNAERFEKLSFEEVIRKGYNIMDMTAFTLCQENNVPIIVFDMNRIGNLEKLVNGNESVGTLIS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MDGP01000001
EMBL· GenBank· DDBJ
OEK03530.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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