A0A1E5LHZ8 · A0A1E5LHZ8_9BACI
- ProteintRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids449 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t6A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) at position 37 in tRNAs that read codons beginning with adenine.
Catalytic activity
- N6-L-threonylcarbamoyladenosine37 in tRNA + [sulfur carrier]-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N6-L-threonylcarbamoyladenosine37 in tRNA + [sulfur carrier]-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H+
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | metal ion binding | |
Molecular Function | N6-threonylcarbomyladenosine methylthiotransferase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus
Accessions
- Primary accessionA0A1E5LHZ8
Proteomes
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length449
- Mass (Da)51,209
- Last updated2017-01-18 v1
- MD5 ChecksumA64069861372081A7D021528577B7531
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MJEH01000010 EMBL· GenBank· DDBJ | OEH93695.1 EMBL· GenBank· DDBJ | Genomic DNA |