A0A1E4SU18 · A0A1E4SU18_9ASCO

Function

function

Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

Catalytic activity

Features

Showing features for active site.

113801002003004005006007008009001,0001,1001,2001,300
TypeIDPosition(s)Description
Active site1111Nucleophile
Active site1229Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionlysophospholipase activity
Biological Processlipid catabolic process
Biological Processphosphatidylcholine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lysophospholipase NTE1
  • EC number
  • Alternative names
    • Intracellular phospholipase B

Gene names

    • ORF names
      CANARDRAFT_209580

Organism names

  • Taxonomic identifier
  • Strain
    • NRRL YB-2248
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Pichiaceae > Ogataea > Ogataea/Candida clade

Accessions

  • Primary accession
    A0A1E4SU18

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-32Helical
Transmembrane38-60Helical
Transmembrane100-120Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain, motif.

TypeIDPosition(s)Description
Region254-275Disordered
Region358-389Disordered
Region407-431Disordered
Compositional bias410-431Basic and acidic residues
Domain548-643Cyclic nucleotide-binding
Domain670-793Cyclic nucleotide-binding
Compositional bias707-733Polar residues
Region707-734Disordered
Domain1078-1242PNPLA
Motif1082-1087GXGXXG
Motif1109-1113GXSXG
Motif1229-1231DGA/G

Sequence similarities

Belongs to the NTE family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,380
  • Mass (Da)
    156,654
  • Last updated
    2017-01-18 v1
  • Checksum
    A2A465C639E73ECC
MTSSTSISIIVTFFNLIGYILYYVPTFIYSILSYTFEIKLSFSTLLIIFFIVITTTYSYIRYKYLTIYSRLPEESKRQEPLIDTFLDTSNQNGRNRSSNFFFYEFLSSIKIFGFLESIVFNELTKSMQTKKLDPGEILFLDEEIGFSICIEGEIEVYCKTGNLSNDQQVTTVFANDNSKETIIIDNIRYQLLNKIKSGSPLSSYISILNLLTTSCEAKNEELGQTKRRSLSSLNNLPLPTDNFQLDSIIDESLDSENEDEDGDNPDKRDYKPPSLIAIPKGHCTISIIPKEAFHRVALKYPKATSHIIQMILTKLYRVTFQTAHDYLGLTVDIMKTELNLNEFKSNKFPHDVLLQQFKKNSSSQQQQQQQQKSENQSNNTNGSSIPRNRSAPTLAEMSIQRPIHQFNNDVEEGNNEEHKSTSHSDEKLRSKNILDDDNESLRLLLAESICEKLGIDQNTIILPKSARKLINNPSVLNSPMISGLGVLKNDNGNLSMSKTKTRTFSTSSQRSTNIKHLRNNSFDESTTTTLLSGNTNGFADFESIKSSIAKEIKIVLLNQGSTIISANEETPGLYYLIDGKLNCSYLKPDNEDESTGEFLYSISPGGIVGYLGTLVGSKSFVDVKCEKESYCAFLSREFFDLLIDKYPYLQLSTAKKLMSLLDMRLLLADYSTEWVHCSAGHPLYTQGDPANGIYIVLNGRFRSIYNPNETNSNSNSNSNLKSNDTNASSKIIGEHGQGESLGEVEVLTKTKRLSTVVAIRDSELARIPRTLFEMIALSNPSIMVKVSRIVAKRVYNRMDNDFINYRIPTIAPSIKDEPLIQSAYNYRTITILPITYGLPVWEFGEKLAIAFEKIGKNVKILNQTSALDRLGKHAFDRLAKLKQNGYFSELEDKYDIVCYIADTPVNSNWTKTCIQQGDCVLLLADSMTSPDIGEYERMLVKSKNAARIELILIHPERTVEPGLTNKWLKNRIWVHSHHHLQMQIHRNKSNLVRHHQEGDNFLFLKTNTLLFKNKLIFETKEKLKNKMELLINNNELFSNVLKQTKESFMSKKYYQPMQEHKDDFMRLARILTGQAIGLVLGGGGARGLSHVGIIKSLESHGIAIDLIGGTSIGAFIGAIYAREYDLVPVYARSKNFSIRMGSIWRSLMDLTIPLTSYLTGHEFNRSIWKVFGDSRIEDFWIKYYANSTNITESLMEIHTSGYAWRYIRASMSLATMFPPLTDNGNMLLDGGYIDNLTVQEMKRRGAKVIIAIDVGSDDDRTLMDYGDSLSGFWVLLNKFNPFSKKPNVPSMTDIQMRLAYVASVNALEKAKATEGCYYMRPPIEGYGTLDFSKFDEIYQVGCNYSDDYFKKLEKNGDLPFLKNKRKEVHRVSGLRRRNSV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias410-431Basic and acidic residues
Compositional bias707-733Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KV453870
EMBL· GenBank· DDBJ
ODV82988.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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