A0A1E3V0E0 · A0A1E3V0E0_9GAMM

  • Protein
    tRNA-dihydrouridine(16) synthase
  • Gene
    dusC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Features

Showing features for site, binding site, active site.

Type
IDPosition(s)Description
Site35Interacts with tRNA; defines subfamily-specific binding signature
Binding site68FMN (UniProtKB | ChEBI)
Site95Interacts with tRNA
Active site98Proton donor
Binding site139FMN (UniProtKB | ChEBI)
Binding site168FMN (UniProtKB | ChEBI)
Site176Interacts with tRNA
Binding site199-201FMN (UniProtKB | ChEBI)
Binding site223-224FMN (UniProtKB | ChEBI)
Site271Interacts with tRNA; defines subfamily-specific binding signature
Site273Interacts with tRNA; defines subfamily-specific binding signature
Site278Interacts with tRNA
Site294Interacts with tRNA; defines subfamily-specific binding signature

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionFMN binding
Molecular FunctiontRNA binding
Molecular FunctiontRNA-dihydrouridine16 synthase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-dihydrouridine(16) synthase
  • EC number
  • Alternative names
    • U16-specific dihydrouridine synthase
      (U16-specific Dus
      )
    • tRNA-dihydrouridine synthase C

Gene names

    • Name
      dusC
    • ORF names
      ABT47_17200

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • T17
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    A0A1E3V0E0

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-297DUS-like FMN-binding

Sequence similarities

Belongs to the Dus family. DusC subfamily.
Belongs to the dus family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    315
  • Mass (Da)
    35,450
  • Last updated
    2017-01-18 v1
  • Checksum
    3E6A0E38D03A781F
MRVILAPMEGVVDDLMRDILSSINPYDLLVTEFVRVVDQLLPEKVFLKLCPELLSGGYTPSVTPVRVQLLGQEPHCMAENAMRAIELGSHGVDANFGCPAKMVNRSNGGAVLLQYPNTIHDIVRAMRQAVPAEHPVTAKIRLGYEDKSLFMENALAVYEAGATELAIHARSKVDGYKPPAYWEYITEVRKRLPIPVIANGEIWNSDDAKRCMEVTGCDSIMIGRGAISLPNLADTIKTGATPYSWADTLQLMLSYTQRELSGRKSDYYPARIKQWFSYLNRQYPEADTLFRELRIYKTTEDIVRVLEQAQQHLSQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LDOA01000001
EMBL· GenBank· DDBJ
ODR86895.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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