A0A1E3S3L3 · A0A1E3S3L3_MYCIE

  • Protein
    Pyridoxal 5'-phosphate synthase subunit PdxT
  • Gene
    pdxT
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site49-51L-glutamine (UniProtKB | ChEBI)
Active site81Nucleophile
Binding site113L-glutamine (UniProtKB | ChEBI)
Binding site141-142L-glutamine (UniProtKB | ChEBI)
Active site177
Active site177Charge relay system
Active site179
Active site179Charge relay system

GO annotations

AspectTerm
Molecular Functionglutaminase activity
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Molecular Functiontransferase activity
Biological Processglutamine catabolic process
Biological Processpyridoxal phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxT
  • EC number
  • Alternative names
    • Pdx2
    • Pyridoxal 5'-phosphate synthase glutaminase subunit
      (EC:3.5.1.2
      ) . EC:3.5.1.2 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      pdxT
    • ORF names
      BHQ20_28595
      , BST27_29010

Organism names

  • Taxonomic identifier
  • Strains
    • HMC2_M5
    • DSM 44049
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium > Mycobacterium simiae complex

Accessions

  • Primary accession
    A0A1E3S3L3

Proteomes

Interaction

Subunit

In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the glutaminase PdxT/SNO family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    198
  • Mass (Da)
    21,197
  • Last updated
    2017-01-18 v1
  • Checksum
    C2C25B208553E6AE
MNRPTVGVLALQGDTREHLIALRECGADPITVRRRSELDAVEALVLPGGESTTMSHLLLELDLLEPLRARLADGLPAYGSCAGMIMLASEIVDAGAGGREALPLRGIDMTVRRNAFGRQVDSFEGDLAFAGLDEPVRAVFIRAPWVERVGDGVQVLARAAGHAVAVRQGSVLATAFHPEMTGDRRIHQLFVDIVTGRA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MIHB01000100
EMBL· GenBank· DDBJ
ODQ96763.1
EMBL· GenBank· DDBJ
Genomic DNA
MVHT01000146
EMBL· GenBank· DDBJ
ORA93294.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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