A0A1E3RUC5 · A0A1E3RUC5_9MYCO
- ProteinPhosphatidylglycerol--prolipoprotein diacylglyceryl transferase
- Genelgt
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids749 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
Catalytic activity
- L-cysteinyl-[prolipoprotein] + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = an S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate + H+
Pathway
Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 145 | a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity | |
Biological Process | lipoprotein biosynthetic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphatidylglycerol--prolipoprotein diacylglyceryl transferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycolicibacterium
Accessions
- Primary accessionA0A1E3RUC5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 24-42 | Helical | |||
Transmembrane | 54-77 | Helical | |||
Transmembrane | 97-117 | Helical | |||
Transmembrane | 124-144 | Helical | |||
Transmembrane | 196-213 | Helical | |||
Transmembrane | 255-273 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 389-422 | Disordered | |||
Compositional bias | 398-422 | Acidic residues | |||
Region | 438-457 | Disordered | |||
Region | 493-749 | Disordered | |||
Compositional bias | 518-538 | Acidic residues | |||
Compositional bias | 572-604 | Acidic residues | |||
Compositional bias | 638-673 | Acidic residues | |||
Sequence similarities
Belongs to the Lgt family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length749
- Mass (Da)77,411
- Last updated2017-01-18 v1
- MD5 ChecksumCFF1A641177C5A511F916E9233185B2E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 398-422 | Acidic residues | |||
Compositional bias | 518-538 | Acidic residues | |||
Compositional bias | 572-604 | Acidic residues | |||
Compositional bias | 638-673 | Acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MIGZ01000084 EMBL· GenBank· DDBJ | ODQ92957.1 EMBL· GenBank· DDBJ | Genomic DNA |