A0A1E3R6H0 · A0A1E3R6H0_9MYCO
- ProteinSulfate adenylyltransferase subunit 2
- GenecysD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids310 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
Catalytic activity
- sulfate + ATP + H+ = adenosine 5'-phosphosulfate + diphosphate
Pathway
Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | sulfate adenylyltransferase (ATP) activity | |
Biological Process | hydrogen sulfide biosynthetic process | |
Biological Process | sulfate assimilation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSulfate adenylyltransferase subunit 2
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycolicibacterium
Accessions
- Primary accessionA0A1E3R6H0
Proteomes
Interaction
Subunit
Heterodimer composed of CysD, the smaller subunit, and CysN.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 41-263 | Phosphoadenosine phosphosulphate reductase | |||
Sequence similarities
Belongs to the PAPS reductase family. CysD subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length310
- Mass (Da)35,510
- Last updated2017-01-18 v1
- Checksum7C99F42451549D63
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MIGZ01000178 EMBL· GenBank· DDBJ | ODQ85546.1 EMBL· GenBank· DDBJ | Genomic DNA |