A0A1E3H8X6 · A0A1E3H8X6_9TREE

Function

function

Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site86Nucleophile
Active site176
Active site178

GO annotations

AspectTerm
Molecular Functionanthranilate synthase activity
Molecular Functionindole-3-glycerol-phosphate synthase activity
Molecular Functionphosphoribosylanthranilate isomerase activity
Biological Processglutamine metabolic process
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional tryptophan biosynthesis protein

Including 3 domains:

  • Recommended name
    Anthranilate synthase component 2
  • EC number
  • Short names
    AS
  • Alternative names
    • Anthranilate synthase, glutamine amidotransferase component
  • Recommended name
    Indole-3-glycerol phosphate synthase
  • EC number
  • Short names
    IGPS
  • Recommended name
    N-(5'-phosphoribosyl)anthranilate isomerase
  • EC number
  • Short names
    PRAI

Gene names

    • ORF names
      L202_08181

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 6039
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus

Accessions

  • Primary accession
    A0A1E3H8X6

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-193Glutamine amidotransferase
Domain240-503Indole-3-glycerol phosphate synthase
Domain583-761N-(5'phosphoribosyl) anthranilate isomerase (PRAI)

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    765
  • Mass (Da)
    81,838
  • Last updated
    2017-01-18 v1
  • Checksum
    21096BD46047DFD4
MGFTLLIDNYDSFTWNIYADIAAIGGNPYVVRNDKITLQEIQKLYETDQIARIVISPGPGHPRTDSGVSRDVIQWGMGKLPIMGVCMGLECLVDCLGGDIGYAGEIMHGKSSFVTHDSIGCFHDLPQDLSSIRYHSLAASISTIPQCLQVTSTSKESGVIMGVRHRVYTVEAVQYHPESCLSEGGKGLMANFLKLKGGKWGGENAWCGVVPEGEASTESAEPKKVNASNGTGAPSLPTILNKIHSQRLQDIDQAKTILSTTPDNVSKSIALHTAPPLISFYDRVKNTPHTAIMAEIKRASPSKGDIAPDASAPEQGLKYALAGASVISVLTEPKWFKGSLIDMLAVRNAVSTLPNRPAILRKDFVLSTYMIDEARLYGADTVLLIVAMLDPDLLSTLYNYSVSLGMEPLVEVNNPTELELALQIGSKVIGVNNRNLHDFNVDMSTTTRVNAALKGRGDVILCALSGISQPEDVETYVKEGVKAVLVGESLMRAKDTGAFLRSLIGLPEPARKQVQEKPLVKICGIRSAKDAQLAIDAGADLLGIILVPGTKRCVSLETAFEIAQVVRTARASRPFPSSPPSIPSSSPEPWFRHNLTTLSSRPKPLLVGVFQNQPLASVIHQTTAIELDLVQLHGDEPQQWAQFIPVPVIKVFRVDDEGKVRGGEVARPGQNSFILLDKGTAQGGGGEGLSFPWKVAKSLISAGEANSLAHPLPVILAGGLTPENVGTAIEETGNGVWCVDVSSGVEGEGGKDEAKVRAFVKAVKG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AWGJ01000014
EMBL· GenBank· DDBJ
ODN72744.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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