A0A1E3H1A0 · A0A1E3H1A0_9HYPH
- ProteinMethionine synthase
- GenemetH_2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids844 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 296 | methylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 363-367 | methylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 366 | Co (UniProtKB | ChEBI) of methylcob(III)alamin (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 411 | methylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 415 | methylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 468 | methylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 554 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 743 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 798-799 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | cobalamin binding | |
Molecular Function | methionine synthase activity | |
Molecular Function | zinc ion binding | |
Biological Process | homocysteine metabolic process | |
Biological Process | methylation | |
Biological Process | tetrahydrofolate metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine synthase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Pleomorphomonadaceae > Methylobrevis
Accessions
- Primary accessionA0A1E3H1A0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-216 | Pterin-binding | |||
Domain | 252-346 | B12-binding N-terminal | |||
Domain | 353-489 | B12-binding | |||
Domain | 504-836 | AdoMet activation | |||
Sequence similarities
Belongs to the vitamin-B12 dependent methionine synthase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length844
- Mass (Da)92,771
- Last updated2017-01-18 v1
- MD5 ChecksumA5A6F5E2B1C9DA4BD4DD1AA94A593E16
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MCRJ01000063 EMBL· GenBank· DDBJ | ODN70072.1 EMBL· GenBank· DDBJ | Genomic DNA |